Research
Research
Current areas of research include:
Occupational Exposures and Pulmonary Adverse Health Outcomes
American Thoracic Society Statement: Occupational contribution to the burden of airway disease.
Balmes J, Becklake M, Blanc P, Henneberger P, Kreiss K, Mapp C, Milton D, Schwartz D, Toren K, Viegi G; Environmental and Occupational Health Assembly, American Thoracic Society. Am J Respir Crit Care Med. 2003;167(5):787-97.
Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease.
Blanc PD, Eisner MD, Earnest G, Trupin L, Balmes JR, Yelin EH, Gregorich SE, Katz PP. J Occup Environ Med. 2009;51(7):804-10.
Chronic obstructive pulmonary disease among residents of an historically industrialised area.
Darby AC, Waterhouse JC, Stevens V, Billings CG, Billings CG, Burton CM, Young C, Wight J, Blanc PD, Fishwick D. Thorax. 2012 Oct;67(10):901-7.
COPD causation and workplace exposures: an assessment of agreement among expert clinical raters.
Fishwick D, Darby A, Hnizdo E, Barber C, Sumner J, Barraclough R, Bolton C, Burge S, Calverley P, Hopkinson N, Hoyle J, Lawson R, Niven R, Pickering T, Prowse K, Reid P, Warburton C, Blanc PD. COPD (J Chronic Obst Pulm Dis) 2013; 10: 172-179.
Gender differences in work-related asthma: surveillance data from California, Massachusetts, Michigan, and New Jersey, 1993-2008.
White GE, Seaman C, Filios MS, Mazurek JM, Flattery J, Harrison RJ, Reilly MJ, Rosenman KD, Lumia ME, Stephens AC, Pechter E, Fitzsimmons K, Davis LK.
J Asthma. 2014 Sep;51(7):691-702
Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008.
Lefkowitz D, Pechter E, Fitzsimmons K, Lumia M, Stephens AC, Davis L, Flattery J, Weinberg J, Harrison RJ, Reilly MJ, Filios MS, White GE, Rosenman KD.
Am J Ind Med. 2015 Nov;58(11):1138-49
The occupational burden of nonmalignant respiratory diseases. An official American Thoracic Society and European Respiratory Society statement.
Blanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Torén K, Vinnikov D, Redlich CA.
Am J Respir Crit Care Med. 2019 199:1312-34.
Highlights from occupational safety and health continuing education needs assessment.
Scott JG, Shore E, Brown C, Harris C, Rosen MA. American Journal of Industrial Medicine. 2019; 62(10):901-907.
Fragrances and work-related asthma-California surveillance data, 1993-2012.
Weinberg JL, Flattery J, Harrison R. J Asthma. 2017;54(10):1041-1050.
Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease.
Blanc PD, Eisner MD, Earnest G, Trupin L, Balmes JR, Yelin EH, Gregorich SE, Katz PP. J Occup Environ Med. 2009;51(7):804-10.
Lung cancer mortality and exposure to synthetic metalworking fluid and biocides: controlling for the healthy worker survivor effect.
Garcia E, Picciotto S, Neophytou AM, Bradshaw PT, Balmes JR, Eisen EA. Occup Environ Med. 2018 Oct;75(10):730-735.
Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort.
Paulin LM, Smith BM, Koch A, Han M, Hoffman EA, Martinez C, Ejike C, Blanc PD, Rous J, Barr RG, Peters SP, Paine R 3rd, Pirozzi C, Cooper CB, Dransfield MT, Comellas AP, Kanner RE, Drummond MB, Putcha N, Hansel NN. Ann Am Thorac Soc. 2018 Dec;15(12):1411-1419.
Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey.
Lytras T, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martinez-Moratalla J, Gullón JA, Pereira-Vega A, Raherison-Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gislason T, Svanes C, Holm M, Forsberg B, Norbäck D, Mehta AJ, Probst-Hensch N, Benke G, Jogi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Vermeulen R, Garcia-Aymerich J, Jarvis D, Zock JP. Thorax. 2018 Nov;73(11):1008-1015.
Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey.
Lytras T, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martínez-Moratalla J, Gullón JA, Vega AP, Raherison Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gíslason T, Svanes Ø, Holm M, Forsberg B, Norbäck D, Mehta AJ, Probst-Hensch N, Benke G, Jogi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Watkins J, Bono R, Buist AS, Vermeulen R, Jarvis D, Zock JP. Occup Environ Med. 2019 Apr;76(4):222-229.
The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement.
Blanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Torén K, Vinnikov D, Redlich CA.
Am J Respir Crit Care Med. 2019 Jun 1;199(11):1312-1334.
Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula.
Neophytou AM, Costello S, Picciotto S, Noth EM, Liu S, Lutzker L, Balmes JR, Hammond K, Cullen MR, Eisen EA. Occup Environ Med. 2019 Dec;76(12):888-894.
Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk.
Torén K, Blanc PD, Naidoo RN, Murgia N, Qvarfordt I, Aspevall O, Dahlman-Hoglund A, Schioler L. Occup Environ Med. 2020 Feb;77(2):57-63.
Smoking, occupational exposures, and idiopathic pulmonary fibrosis among Swedish construction workers.
Andersson M, Blanc PD, Torén K, Järvholm B. Am J Ind Med. 2021 Apr;64(4):251-257.
Occupation versus environmental factors in hypersensitivity pneumonitis: population attributable fraction.
Barnes H, Olin AC, Torén K, McSharry C, Donnelly I, Lärstad M, Iribarren C, Quinlan P, Blanc PD. ERJ Open Res. 2020 Oct 5;6(4):00374-2020.
The hidden history of hypersensitivity pneumonitis.
Barnes H, Jones K, Blanc P. Eur Respir J. 2021 Jun 3:2100252.
Cumulative occupational exposures and lung-function decline in two large general-population cohorts.
Lytras T, Beckmeyer-Borowko A, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martínez-Moratalla J, Gullón JA, Pereira Vega A, Raherison Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gislason T, Svanes Ø, Holm M, Forsberg B, Norbäck D, Mehta AJ, Keidel D, Vernez D, Benke G, Jõgi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Watkins J, Bono R, Squillacioti G, Buist AS, Vermeulen R, Jarvis D, Probst-Hensch N, Zock JP.
Ann Am Thorac Soc. 2021 Feb;18(2):238-246.
Becoming disenthralled with our conventional understanding of occupational lung disease.
Blanc PD. Respirology. 2022 Jun;27(6):383-384.
Rare case of occupational pulmonary hemorrhage in a firefighter.
Gandhi SA, Welch TJ, Jones KD, Cummings KJ, Styles L, Blanc PD, Harrison RJ. Respir Med Case Rep. 2022 Aug 4;39:101722.
Occupational and Environmental Exposures through Military Service
Diagnosing chronic obstructive pulmonary disease among Afghanistan and Iraq veterans: Veterans Affair's concordance with clinical guidelines for spirometry administration.
Schneiderman AI, Dougherty DD, Fonseca VP, Wolters CL, Bossarte RM, Arjomandi M. Mil Med. 2017;182(9):e1993-e2000.
Respiratory health after military service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop report.
Garshick E, Abraham JH, Baird CP, Ciminera P, Downey GP, Falvo MJ, Hart JE, Jackson DA, Jerrett M, Kuschner W, Helmer DA, Jones KD, Krefft SD, Mallon T, Miller RF, Morris MJ, Proctor SP, Redlich CA, Rose CS, Rull RP, Saers J, Schneiderman AI, Smith NL, Yiallouros P, Blanc PD. Ann Am Thorac Soc. 2019 Aug;16(8):e1-e16.
Military deployment and respiratory symptoms: Some answers, many questions.
Garshick E, Blanc PD. Chest. 2020 Jun;157(6):1407-1408.
Military burn pits.
Sotolongo A, Falvo M, Santos S, Johnson I, Arjomandi M, Hines S, Krefft S, Osterholzer J. Am J Respir Crit Care Med. 2020 Apr 1;201(7):P13-P14.
Inorganic dust exposure during military service as a predictor of rheumatoid arthritis and other autoimmune conditions.
Ying D, Schmajuk G, Trupin L, Blanc PD. ACR Open Rheumatol. 2021 Jul;3(7):466-474.
Military service and COPD risk.
Trupin L, Schmajuk G, Ying D, Yelin E, Blanc PD. Chest. 2022 Oct;162(4):792-795.
Consensus statements on deployment-related respiratory disease, inclusive of constrictive bronchiolitis: A modified Delphi study.
Falvo MJ, Sotolongo AM, Osterholzer JJ, Robertson MW, Kazerooni EA, Amorosa JK, Garshick E, Jones KD, Galvin JR, Kreiss K, Hines SE, Franks TJ, Miller RF, Rose CS, Arjomandi M, Krefft SD, Morris MJ, Polosukhin VV, Blanc PD, D'Armiento JM. Chest. 2022 Nov 4:S0012-3692(22)04047-8.
Postdeployment respiratory health: The roles of the airborne hazards and open burn pit registry and the post-deployment cardiopulmonary evaluation network.
Davis CW, Rabin AS, Jani N, Osterholzer JJ, Krefft S, Hines SE, Arjomandi M, Robertson MW, Sotolongo AM, Falvo MJ; Post-Deployment Cardiopulmonary Evaluation Network. Fed Pract. 2022 Aug;39(8):337-343.
Agent Orange exposure and risk of idiopathic pulmonary fibrosis among U.S. Veterans.
Kaul B, Lee JS, Glidden DV, Blanc PD, Zhang N, Collard HR, Whooley MA. Am J Respir Crit Care Med. 2022 Sep 15;206(6):750-757.
Military deployment-related respiratory problems: an update.
Garshick E, Blanc PD. Curr Opin Pulm Med. 2023 Mar 1;29(2):83-89.
Wildland Fire Health Affects
Differential respiratory health effects from the 2008 northern California wildfires: A spatiotemporal approach.
Reid CE, Jerrett M, Tager IB, Petersen ML, Mann JK, Balmes JR. Environ Res. 2016 Oct;150:227-35.
Critical review of health impacts of wildfire smoke exposure.
Reid CE, Brauer M, Johnston FH, Jerrett M, Balmes JR, Elliott CT. Environ Health Perspect. 2016 Sep;124(9):1334-43.
Occupational exposure to polycyclic aromatic hydrocarbon of wildland firefighters at prescribed and wildland fires.
Navarro KM, Cisneros R, Noth EM, Balmes JR, Hammond SK. Environ Sci Technol. 2017 Jun 6;51(11):6461-6469.
Where there's wildfire, there's smoke.
Balmes JR. N Engl J Med. 2018 Mar 8;378(10):881-883.
Cardiovascular and cerebrovascular emergency department visits associated with wildfire smoke exposure in California in 2015.
Wettstein ZS, Hoshiko S, Fahimi J, Harrison RJ, Cascio WE, Rappold AG. J Am Heart Assoc. 2018 Apr 11;7(8).
Wildland firefighter smoke exposure and risk of lung cancer and cardiovascular disease mortality.
Navarro KM, Kleinman MT, Mackay CE, Reinhardt TE, Balmes JR, Broyles GA, Ottmar RD, Naher LP, Domitrovich JW. Environ Res. 2019 Jun;173:462-468.
Incident command post exposure to polycyclic aromatic hydrocarbons and particulate matter during a wildfire.
Navarro KM, Cisneros R, Schweizer D, Chowdhary P, Noth EM, Balmes JR, Hammond SK. J Occup Environ Hyg. 2019 Nov;16(11):735-744.
The hazards of wildfire smoke exposure for children.
Hauptman M, Balmes JR, Miller MD. Curr Probl Pediatr Adolesc Health Care. 2020 Feb;50(2):100756.
Differences in the estimation of wildfire-associated air pollution by satellite mapping of smoke plumes and ground-level monitoring.
Fadadu RP, Balmes JR, Holm SM. Int J Environ Res Public Health. 2020 Nov 5;17(21):8164.
The changing nature of wildfires: impacts on the health of the public.
Balmes JR. Clin Chest Med. 2020 Dec;41(4):771-776.
Health effects of wildfire smoke in children and public health tools: a narrative review.
Holm SM, Miller MD, Balmes JR. J Expo Sci Environ Epidemiol. 2021 Feb;31(1):1-20.
Coccidioidomycosis outbreak among inmate wildland firefighters: California, 2017.
Laws RL, Jain S, Cooksey GS, Mohle-Boetani J, McNary J, Wilken J, Harrison R, Leistikow B, Vugia DJ, Windham GC, Materna BL. Am J Ind Med. 2021 Apr;64(4):266-273.
Association of wildfire air pollution and health care use for atopic dermatitis and itch.
Fadadu RP, Grimes B, Jewell NP, Vargo J, Young AT, Abuabara K, Balmes JR, Wei ML. JAMA Dermatol. 2021 Jun 1;157(6):658-666.
Respiratory impacts of wildland fire smoke: future challenges and policy opportunities. An official American Thoracic Society workshop report.
Rice MB, Henderson SB, Lambert AA, Cromar KR, Hall JA, Cascio WE, Smith PG, Marsh BJ, Coefield S, Balmes JR, Kamal A, Gilmour MI, Carlsten C, Navarro KM, Collman GW, Rappold A, Miller MD, Stone SL, Costa DL. Ann Am Thorac Soc. 2021 Jun;18(6):921-930.
Fire and water: assessing drinking water contamination after a major wildfire.
Solomon GM, Hurley S, Carpenter C, Young TM, English P, Reynolds P. ACS ES T Water. 2021 Aug 13;1(8):1878-1886.
Wildland firefighter exposure to smoke and COVID-19: A new risk on the fire line.
Navarro KM, Clark KA, Hardt DJ, Reid CE, Lahm PW, Domitrovich JW, Butler CR, Balmes JR. Sci Total Environ. 2021 Mar 15;760:144296.
Organic chemical contaminants in water system infrastructure following wildfire.
Draper WM, Li N, Solomon GM, Heaney YC, Crenshaw RB, Hinrichs RL, Chandrasena REP. ACS ES T Water. 2022 Feb 11;2(2):357-366.
Tuberculosis diagnoses following wildfire smoke exposure in California.
Linde LR, Readhead A, Barry PM, Balmes JR, Lewnard JA. Am J Respir Crit Care Med. 2023 Feb 1;207(3):336-345.
Impact of Environmental Exposures, Including Ambient and Indoor Air Pollution, on Pulmonary Outcomes
Mediators of the socioeconomic gradient in outcomes of adult asthma and rhinitis.
Trupin L, Katz PP, Balmes JR, Chen H, Yelin EH, Omachi T, Blanc PD. Am J Public Health. 2013;103(2):e31-8.
Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration.
Van Dyken SJ, Garcia D, Porter P, Huang X, Quinlan PJ, Blanc PD, Corry DB, Locksley RM. J Immunol. 2011;187(5):2261-7.
Annual average ambient particulate matter exposure estimates, measured home particulate matter, and hair nicotine are associated with respiratory outcomes in adults with asthma.
Balmes JR, Cisternas M, Quinlan PJ, Trupin L, Lurmann FW; Katz PP, Blanc PD. Environ Res 2014;129: 1-10.
Outdoor air pollution and asthma.
Guarnieri M, Balmes JR. Lancet. 2014 May 3;383(9928):1581-92
Chronic obstructive pulmonary disease among residents of an historically industrialised area.
Darby AC, Waterhouse JC, Stevens V, Billings CG, Billings CG, Burton CM, Young C, Wight J, Blanc PD, Fishwick D. Thorax. 2012;67(10):901-7.
Investigation of hydrogen sulfide exposure and lung function, asthma and chronic obstructive pulmonary disease in a geothermal area of New Zealand.
Bates MN, Crane J, Balmes JR, Garrett N. PLoS One. 2015;10(3):e0122062.
High risks of lung disease associated with early-life and moderate lifetime arsenic exposure in northern Chile.
Steinmaus C, Ferreccio C, Acevedo J, Balmes JR, Liaw J, Troncoso P, Dauphiné DC, Nardone A, Smith AH. Toxicol Appl Pharmacol. 2016;313:10-15.
AJRCCM: 100-year anniversary. Clearing the air: indoors, outdoors, and at work.
Balmes JR.Am J. Respir Crit Care Med. 2017 May 1;195(9):1100-1103.
Cookstove trials and tribulations: What Is needed to decrease the burden of household air pollution?
Mortimer K, Balmes JR. Ann Am Thorac Soc. 2018 May;15(5):539-541.
Air pollution exposure is associated with lower lung function, but not changes in lung function, in patients with idiopathic pulmonary fibrosis.
Johannson KA, Vittinghoff E, Morisset J, Wolters PJ, Noth EM, Balmes JR, Collard HR. Chest. 2018 Jul;154(1):119-125.
Exposure to household air pollution from biomass cookstoves and levels of fractional exhaled nitric oxide (FeNO) among Honduran women.
Benka-Coker ML, Clark ML, Rajkumar S, Young BN, Bachand AM, Balmes JR, Brook R, Nelson TL, Volckens J, Reynolds SJ, Wilson A, L'Orange C, Good N, Quinn C, Koehler K, Africano S, Osorto Pinel A, Peel JL. Int J Environ Res Public Health. 2018 Nov 13;15(11):2544.
Air pollution and noncommunicable diseases: A review by the Forum of International Respiratory Societies' Environmental Committee, Part 2: Air pollution and organ systems.
Schraufnagel DE, Balmes JR, Cowl CT, De Matteis S, Jung SH, Mortimer K, Perez-Padilla R, Rice MB, Riojas-Rodriguez H, Sood A, Thurston GD, To T, Vanker A, Wuebbles DJ. Chest. 2019 Feb;155(2):417-426.
Air pollution and noncommunicable diseases: A review by the Forum of International Respiratory Societies' Environmental Committee, Part 1: The damaging effects of air pollution.
Schraufnagel DE, Balmes JR, Cowl CT, De Matteis S, Jung SH, Mortimer K, Perez-Padilla R, Rice MB, Riojas-Rodriguez H, Sood A, Thurston GD, To T, Vanker A, Wuebbles DJ. Chest. 2019 Feb;155(2):409-416.
Low to moderate air pollutant exposure and acute respiratory distress syndrome after severe trauma.
Reilly JP, Zhao Z, Shashaty MGS, Koyama T, Christie JD, Lanken PN, Wang C, Balmes JR, Matthay MA, Calfee CS, Ware LB.
Am J Respir Crit Care Med. 2019 Jan 1;199(1):62-70.
Household air pollution from domestic combustion of solid fuels and health.
Balmes JR. J Allergy Clin Immunol. 2019 Jun;143(6):1979-1987.
Health benefits of air pollution reduction.
Schraufnagel DE, Balmes JR, De Matteis S, Hoffman B, Kim WJ, Perez-Padilla R, Rice M, Sood A, Vanker A, Wuebbles DJ. Ann Am Thorac Soc. 2019 Dec;16(12):1478-1487.
Inhaled corticosteroids use and risk of invasive pneumococcal disease in a population-based study.
Torén K, Blanc PD, Qvarfordt I, Aspevall O, Schiöler L. Ann Am Thorac Soc. 2020 Dec;17(12):1570-1575.
Cardiopulmonary impact of particulate air pollution in high-risk populations: JACC State-of-the-Art Review.
Newman JD, Bhatt DL, Rajagopalan S, Balmes JR, Brauer M, Breysse PN, Brown AGM, Carnethon MR, Cascio WE, Collman GW, Fine LJ, Hansel NN, Hernandez A, Hochman JS, Jerrett M, Joubert BR, Kaufman JD, Malik AO, Mensah GA, Newby DE, Peel JL, Siegel J, Siscovick D, Thompson BL, Zhang J, Brook RD.
J Am Coll Cardiol. 2020 Dec 15;76(24):2878-2894.
Biomass fuel use and cardiac function in Nepali women.
Tiwana J, Benziger C, Hooper L, Pope K, Alurkar V, Kafle R, Sijali TR, Balmes JR, Kaufman JD, Bates MN. Glob Heart. 2020 Feb 7;15(1):11.
Guidance to reduce the cardiovascular burden of ambient air pollutants: A policy statement from the American Heart Association.
Kaufman JD, Elkind MSV, Bhatnagar A, Koehler K, Balmes JR, Sidney S, Burroughs Peña MS, Dockery DW, Hou L, Brook RD, Laden F, Rajagopalan S, Bishop Kendrick K, Turner JR; American Heart Association Advocacy Coordinating Committee. Circulation. 2020 Dec 8;142(23):e432-e447.
Outdoor air pollution and new-onset airway disease. An official American Thoracic Society workshop report.
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW. Ann Am Thorac Soc. 2020 Apr;17(4):387-398.
Associations between historical residential redlining and current age-adjusted rates of emergency department visits due to asthma across eight cities in California: an ecological study.
Nardone A, Casey JA, Morello-Frosch R, Mujahid M, Balmes JR, Thakur N. Lancet Planet Health. 2020 Jan;4(1):e24-e31.
Non-communicable respiratory disease and air pollution exposure in Malawi: a prospective cohort study.
Rylance S, Jewell C, Naunje A, Mbalume F, Chetwood JD, Nightingale R, Zurba L, Flitz G, Gordon SB, Lesosky M, Balmes JR, Mortimer K. Thorax. 2020 Mar;75(3):220-226.
Inhaled corticosteroid (ICS) use and invasive pneumococcal pneumonia.
Torén K, Blanc PD, Murgia N, Stockfelt L, Schiöler L. Ann Am Thorac Soc. 2021 Aug 19.
Place matters: residential racial segregation and COPD.
Balmes JR. Am J Respir Crit Care Med. 2021 Sep 1;204(5):496-498.
The air we breathe: Respiratory impact of indoor air quality in chronic obstructive pulmonary disease.
Mkorombindo T, Balmes JR, Custovic A, Dransfield MT. Am J Respir Crit Care Med. 2022 Feb 15;205(4):378-380.
Household air pollution and COPD: cause and effect or confounding by other aspects of poverty?
Mortimer K, Montes de Oca M, Salvi S, Balakrishnan K, Hadfield RM, Ramirez-Venegas A, Halpin DMG, Ozoh Obianuju B, Han MeiLan K, Perez Padilla R, Kirenga B, Balmes JR. Int J Tuberc Lung Dis. 2022 Mar 1;26(3):206-216.
Air pollution and atopic dermatitis, from molecular mechanisms to population-level evidence: A review.
Fadadu RP, Abuabara K, Balmes JR, Hanifin JM, Wei ML. Int J Environ Res Public Health. 2023 Jan 31;20(3):2526.
Cooking with natural gas: Just the facts please.
Balmes JR, Holm SM, McCormack MC, Hansel NN, Gerald LB, Krishnan JA. Am J Respir Crit Care Med. 2023 Mar 3.
Cardiopulmonary Health Effects of Exposure to Ozone
Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome.
Ware LB, Zhao Z, Koyama T, May AK, Matthay MA, Lurmann FW, Balmes JR, Calfee CS. Am J Respir Crit Care Med. 2016;193(10):1143-50.
Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adults.
Chen C, Arjomandi M, Balmes J, Tager I, Holland N. Environ Health Perspect. 2007;115(12):1732-7.
Ozone inhalation leads to a dose-dependent increase of cytogenetic damage in human lymphocytes.
Holland N, Davé V, Venkat S, Wong H, Donde A, Balmes JR, Arjomandi M. Environ Mol Mutagen. 2015; 56(4):378-87.
Exposure to medium and high ambient levels of ozone causes adverse systemic inflammatory and cardiac autonomic effects.
Arjomandi M, Wong H, Donde A, Frelinger J, Dalton S, Ching W, Power K, Balmes JR. Am J Physiol Heart Circ Physiol. 2015; 308(12):H1499-509.
Inflammatory and repair pathways induced in human bronchoalveolar lavage cells with ozone inhalation.
Leroy P, Tham A, Wong H, Tenney R, Chen C, Stiner R, Balmes JR, Paquet AC, Arjomandi M. PLoS One. 2015;10(6):e0127283.
Modeling vascular inflammation and atherogenicity after inhalation of ambient levels of ozone: exploratory lessons from transcriptomics.
Tham A, Lullo D, Dalton S, Zeng S, van Koeverden I, Arjomandi M. Inhal Toxicol. 2017;29(3):96-105.
Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of exposure to low concentrations of ozone on respiratory and cardiovascular outcomes.
Frampton MW, Balmes JR, Bromberg PA, Stark P, Arjomandi M, Hazucha MJ, Rich DQ, Hollenbeck-Pringle D, Dagincourt N, Alexis N, Ganz P, Zareba W, Costantini MG.
Res Rep Health Eff Inst. 2017 Jun;(192, Pt 1):1-107.
EPA's new ozone air quality standard: why should we care?
Balmes JR. Ann Am Thorac Soc. 2017 Nov;14(11):1627-1629.
Respiratory responses to ozone exposure. MOSES (The Multicenter Ozone Study in Older Subjects).
Arjomandi M, Balmes JR, Frampton MW, Bromberg P, Rich DQ, Stark P, Alexis NE, Costantini M, Hollenbeck-Pringle D, Dagincourt N, Hazucha MJ.
Am J Respir Crit Care Med. 2018;197(10):1319-1327.
Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES).
Rich DQ, Balmes JR, Frampton MW, Zareba W, Stark P, Arjomandi M, Hazucha MJ, Costantini MG, Ganz P, Hollenbeck-Pringle D, Dagincourt N, Bromberg PA.
Environ Int. 2018 Oct;119:193-202.
Long-term exposure to ozone and cardiopulmonary mortality: epidemiology strikes again.
Balmes JR. Am J Respir Crit Care Med. 2019 Oct 15;200(8):958-959.
Ozone effects on blood biomarkers of systemic inflammation, oxidative stress, endothelial function, and thrombosis: The Multicenter Ozone Study in oldEr Subjects (MOSES).
Balmes JR, Arjomandi M, Bromberg PA, Costantini MG, Dagincourt N, Hazucha MJ, Hollenbeck-Pringle D, Rich DQ, Stark P, Frampton MW.
PLoS One. 2019 Sep 25;14(9):e0222601.
Do ambient ozone or other pollutants modify effects of controlled ozone exposure on pulmonary function?
Rich DQ, Thurston SW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Alexis NE, Ganz P, Zareba W, Thevenet-Morrison K, Koutrakis P, Frampton MW.
Ann Am Thorac Soc. 2020 May;17(5):563-572.
Multicenter Ozone Study in oldEr Subjects (MOSES): Part 2. Effects of personal and ambient concentrations of ozone and other pollutants on cardiovascular and pulmonary function.
Rich DQ, Frampton MW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Thurston SW, Alexis NE, Ganz P, Zareba W, Koutrakis P, Thevenet-Morrison K.
Res Rep Health Eff Inst. 2020 Mar;(192, Pt 2):1-90.
Long-term ozone exposure is positively associated with telomere length in critically ill patients.
Wang C, Wolters PJ, Calfee CS, Liu S, Balmes JR, Zhao Z, Koyama T, Ware LB.
Environ Int. 2020 Aug;141:105780.
Geospatial-temporal analysis of the impact of ozone on asthma rescue inhaler use.
Pepper JR, Barrett MA, Su JG, Merchant R, Henderson K, Van Sickle D, Balmes JR.
Environ Int. 2020 Mar;136:105331.
Systematic review of ozone effects on human lung function, 2013-2020.
Holm SM, Balmes JR.
Chest. 2021 Aug 10:S0012-3692(21)03626-6.
Systematic review of ozone effects on human lung function, 2013 through 2020.
Holm SM, Balmes JR. Chest. 2022 Jan;161(1):190-201.
Long-term exposure to ozone and small airways: A large impact?
Balmes JR. Am J Respir Crit Care Med. 2022 Feb 15;205(4):384-385.
Effect of ozone on allergic airway inflammation.
Arjomandi M, Wong H, Tenney R, Holland N, Balmes JR. J Allergy Clin Immunol Glob. 2022 Nov;1(4):273-281.
Effects of short-term increases in personal and ambient pollutant concentrations on pulmonary and cardiovascular function: A panel study analysis of the Multicenter Ozone Study in oldEr subjects (MOSES 2).
Frampton MW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Thurston SW, Alexis NE, Ganz P, Zareba W, Koutrakis P, Thevenet-Morrison K, Rich DQ. Environ Res. 2022 Apr 1;205:112522.
Lifestyle Factors and COPD
The role of physical inactivity in increasing disability among older adults with obstructive airway disease.
Katz P, Chen H, Omachi TA, Gregorich SE, Julian L, Cisternas M, Balmes J, Blanc PD. J Cardiopulm Rehabil Prev. 2011;31(3):193-7.
Disability in valued life activities among individuals with COPD and other respiratory conditions.
Katz PP, Gregorich S, Eisner M, Julian L, Chen H, Yelin E, Blanc PD. J Cardiopulm Rehabil Prev. 2010;30(2):126-36.
Lower health literacy is associated with poorer health status and outcomes in chronic obstructive pulmonary disease.
Omachi TA, Sarkar U, Yelin EH, Blanc PD, Katz PP. J. Gen Intern Med. 2013;28(1):74-81.
Obesity and functioning among individuals with chronic obstructive pulmonary disease (COPD).
Katz P, Iribarren C, Sanchez G, Blanc PD. COPD (J Chronic Obst Pulm Dis) 2016;13:352-9.
Cigarette and Cannabis Smoke Exposure
Directly measured secondhand smoke exposure and COPD health outcomes.
Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD. BMC Pulm Med. 2006;6:12.
Pulmonary function abnormalities in never-smoking flight attendants exposed to secondhand tobacco smoke in the aircraft cabin.
Arjomandi M, Haight T, Redberg R, Gold WM. J. Occup Environ Med. 2009;51(6):639-46.
Reduced exercise tolerance and pulmonary capillary recruitment with remote secondhand smoke exposure.
Arjomandi M, Haight T, Sadeghi N, Redberg R, Gold WM. PLoS One. 2012;7(4):e34393.
Secondhand tobacco smoke and COPD risk in smokers: A COPDGene Study cohort subgroup analysis.
Koeverden IV, Blanc PD, Bowler RP, Arjomandi M. COPD. 2015; 2(2):182-9.
Impairment of endothelial function by little cigar secondhand smoke.
Liu J, Wang X, Narayan S, Glantz SA, Schick SF, Springer ML. Tob Regul Sci. 2016;2(1):56-63.
From the cover: Thirdhand cigarette smoke causes stress-induced mitochondrial hyperfusion and alters the transcriptional profile of stem cells.
Bahl V, Johnson K, Phandthong R, Zahedi A, Schick SF, Talbot P. Toxicol Sci. 2016;153(1):55-69.
Thirdhand smoke: new evidence, challenges, and future directions.
Jacob P 3rd, Benowitz NL, Destaillats H, Gundel L, Hang B, Martins-Green M, Matt GE, Quintana PJ, Samet JM, Schick SF, Talbot P, Aquilina NJ, Hovell MF, Mao JH, Whitehead TP. Chem Res Toxicol. 2017;30(1):270-294
Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice.
Hang B, Snijders AM, Huang Y, Schick SF, Wang P, Xia Y, Havel C, Jacob P 3rd, Benowitz N, Destaillats H, Gundel LA, Mao JH.
Sci Rep. 2017 Feb 3;7:41915.
Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice.
Gotts JE, Chun L, Abbott J, Fang X, Takasaka N, Nishimura SL, Springer ML, Schick SF, Calfee CS, Matthay MA.
Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L25-L40.
Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction.
Arjomandi M, Zeng S, Geerts J, Stiner RK, Bos B, van Koeverden I, Keene J, Elicker B, Blanc PD, Gold WM. BMJ Open Respir Res. 2018; 5(1):e000284
Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice.
Hang B, Wang Y, Huang Y, Wang P, Langley SA, Bi L, Sarker AH, Schick SF, Havel C, Jacob P 3rd, Benowitz N, Destaillats H, Tang X, Xia Y, Jen KY, Gundel LA, Mao JH, Snijders AM. Clin Sci (Lond). 2018;132(4):475-488.
Exposure to second-hand tobacco smoke and respiratory symptoms in non-smoking adults: cross-sectional data from the general population of Telemark, Norway.
Fell AKM, Svendsen MV, Kim JL, Abrahamsen R, Henneberger PK, Torén K, Blanc PD, Kongerud J. BMC Public Health. 2018 18:843.
Marijuana use, respiratory symptoms, and pulmonary function: a systematic review and meta-analysis.
Ghasemiesfe M, Ravi D, Vali M, Korenstein D, Arjomandi M, Frank J, Austin PC, Keyhani S. Ann Intern Med. 2018 Jul 17;169(2):106-115.
Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma.
Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG.
Thorax. 2018 Nov;73(11):1041-1048.
Assessing toxicity and in vitro bioactivity of smoked cigarette leachate using cell-based assays and chemical analysis.
Xu EG, Richardot WH, Li S, Buruaem L, Wei HH, Dodder NG, Schick SF, Novotny T, Schlenk D, Gersberg RM, Hoh E. Chem Res Toxicol. 2019 Aug 19;32(8):1670-1679.
Thirdhand smoke exposure causes replication stress and impaired transcription in human lung cells.
Sarker AH, Trego KS, Zhang W, Jacob P 3rd, Snijders AM, Mao JH, Schick SF, Cooper PK, Hang B.
Environ Mol Mutagen. 2020 Jul;61(6):635-646.
Smoking practices in relation to exhaled carbon monoxide in an occupational cohort.
Vinnikov D, Tulekov Z, Romanova Z, Krugovykh I, Blanc PD.
BMC Public Health. 2020 Dec 9;20(1):1894.
Adhesion and removal of thirdhand smoke from indoor fabrics: a method for rapid assessment and identification of chemical repositories.
Pozuelos GL, Jacob P 3rd, Schick SF, Omaiye EE, Talbot P.
Int J Environ Res Public Health. 2021 Mar 30;18(7):3592.
In utero and early-life exposure to thirdhand smoke causes profound changes to the immune system.
Snijders AM, Zhou M, Whitehead TP, Fitch B, Pandey P, Hechmer A, Huang A, Schick SF, de Smith AJ, Olshen AB, Metayer C, Mao JH, Wiemels JL, Kogan SC.
Clin Sci (Lond). 2021 Apr 30;135(8):1053-1063.
Thirdhand cigarette smoke leads to age-dependent and persistent alterations in the cecal microbiome of mice.
He L, Zhou YX, Zhang Y, Hang B, Chang H, Schick SF, Celniker SE, Xia Y, Snijders AM, Mao JH.
Microbiologyopen. 2021 Jun;10(3):e1198.
Genetic background influences the effect of thirdhand smoke exposure on anxiety and memory in Collaborative Cross mice.
He L, Wang P, Schick SF, Huang A, Jacob P 3rd, Yang X, Xia Y, Snijders AM, Mao JH, Chang H, Hang B.
Sci Rep. 2021 Jun 24;11(1):13285.
PM2.5 Concentrations in a Cannabis Store with On-Site Consumption.
Murphy MB, Huang AS, Schick SF.
Environ Health Perspect. 2021 Jun;129(6):67701.
Remote exposure to secondhand tobacco smoke is associated with lower exercise capacity through effects on oxygen pulse, a proxy of cardiac stroke volume.
Zeng S, Dunn M, Gold WM, Kizer JR, Arjomandi M. BMJ Open Respir Res. 2022 May;9(1):e001217.
Elastin degradation and lung function deterioration with remote secondhand tobacco smoke exposure in never-smokers.
Mustra Rakic J, Zeng S, Rohdin-Bibby L, Van Blarigan EL, Liu X, Ma S, Kane JP, Redberg RF, Turino GM, Oestreicher Stock E, Arjomandi M. Chronic Obstr Pulm Dis. 2022 Jul 29;9(3):377-393.
Thirdhand exposures to tobacco-specific nitrosamines through inhalation, dust ingestion, dermal uptake, and epidermal chemistry.
Tang X, Benowitz N, Gundel L, Hang B, Havel CM, Hoh E, Jacob Iii P, Mao JH, Martins-Green M, Matt GE, Quintana PJE, Russell ML, Sarker A, Schick SF, Snijders AM, Destaillats H. Environ Sci Technol. 2022 Sep 6;56(17):12506-12516.
Dermal thirdhand smoke exposure induces oxidative damage, initiates skin inflammatory markers, and adversely alters the human plasma proteome.
Sakamaki-Ching S, Schick S, Grigorean G, Li J, Talbot P. EBioMedicine. 2022 Oct;84:104256.
Impairment of endothelial function by cigarette smoke is not caused by a specific smoke constituent, but by vagal input from the airway.
Nabavizadeh P, Liu J, Rao P, Ibrahim S, Han DD, Derakhshandeh R, Qiu H, Wang X, Glantz SA, Schick SF, Springer ML. I Arterioscler Thromb Vasc Biol. 2022 Nov;42(11):1324-1332.
Respiratory exposure to thirdhand cigarette smoke increases concentrations of urinary metabolites of nicotine.
Pratt K, Hilty A, Jacob P, Schick SF. Nicotine Tob Res. 2023 Jan 7:ntad002.
E-cigarettes & Vaping
A device-independent evaluation of carbonyl emissions from heated electronic cigarette solvents.
Wang P, Chen W, Liao J, Matsuo T, Ito K, Fowles J, Shusterman D, Mendell M, Kumagai K.
PLoS One. 2017 Jan 11;12(1):e0169811.
E-cigarettes versus nicotine patches for perioperative smoking cessation: a pilot randomized trial.
Lee SM, Tenney R, Wallace AW, Arjomandi M.
Peer J. 2018 Sep 28;6:e5609.
Measurement of heating coil temperature for e-cigarettes with a "top-coil" clearomizer.
Chen W, Wang P, Ito K, Fowles J, Shusterman D, Jaques PA, Kumagai K.
PLoS One. 2018 Apr 19;13(4):e0195925.
Modeling cardiovascular risks of E-cigarettes with human-induced pluripotent stem cell-derived endothelial cells.
Lee WH, Ong SG, Zhou Y, Tian L, Bae HR, Baker N, Whitlatch A, Mohammadi L, Guo H, Nadeau KC, Springer ML, Schick SF, Bhatnagar A, Wu JC.
J Am Coll Cardiol. 2019 Jun 4;73(21):2722-2737.
Characteristics of a multistate outbreak of lung injury associated with E-cigarette use, or vaping - United States, 2019.
Perrine CG, Pickens CM, Boehmer TK, King BA, Jones CM, DeSisto CL, Duca LM, Lekiachvili A, Kenemer B, Shamout M, Landen MG, Lynfield R, Ghinai I, Heinzerling A, Lewis N, Pray IW, Tanz LJ, Patel A, Briss PA; Lung Injury Response Epidemiology/Surveillance Group. MMWR Morb Mortal Wkly Rep. 2019 Oct 4;68(39):860-864.
Vaping-induced acute lung injury: an epidemic that could have been prevented.
Balmes JR. Am J Respir Crit Care Med. 2019 Dec 1;200(11):1342-1344.
Notes from the field: characteristics of E-cigarette, or vaping, Products confiscated in public high schools in California and North Carolina - March and May 2019.
Shamout M, Tanz L, Herzig C, Oakley LP, Peak CM, Heinzerling A, Hast M, McGowan E, Williams RJ, Hess C, Wang C, Planche S, Herndon S, Martin J, Kansagra SM, Al-Shawaf M, Melstrom P, Marynak K, Tynan MA, Agaku IT, King BA. MMWR Morb Mortal Wkly Rep. 2020 Oct 23;69(42):1552-1554.
Notes from the field: E-cigarette, or vaping, product use-associated lung injury cases during the COVID-19 response - California, 2020.
Armatas C, Heinzerling A, Wilken JA. MMWR Morb Mortal Wkly Rep. 2020 Jun 26;69(25):801-802.
Severe lung injury associated with use of e-Cigarette, or vaping, product s- California, 2019.
Heinzerling A, Armatas C, Karmarkar E, Attfield K, Guo W, Wang Y, Vrdoljak G, Moezzi B, Xu D, Wagner J, Fowles J, Dean C, Cummings KJ, Wilken JA.
JAMA Intern Med. 2020 Jun 1;180(6):861-869.
Chemical composition of JUUL pods collected from students in California high schools.
Shamout M, Wang P, Wong F, Chen W, Kumagai K, Pérez JJ, Watson CH, Valentín-Blasini L, Tanz L, Herzig C, Oakley LP, Peak CM, Heinzerling A, Williams RJ, Hess C, Wang C, Planche S, Al-Shawaf M, Melstrom P, Marynak K, Tynan MA, Agaku IT, King BA. J Adolesc Health. 2021 Aug;69(2):342-345.
Chronic E-cigarette use impairs endothelial function on the physiological and cellular levels.
Mohammadi L, Han DD, Xu F, Huang A, Derakhshandeh R, Rao P, Whitlatch A, Cheng J, Keith RJ, Hamburg NM, Ganz P, Hellman J, Schick SF, Springer ML. Arterioscler Thromb Vasc Biol. 2022 Nov;42(11):1333-1350.
Disability and Health Outcomes of Obstructive Lung Disease and Sleep Apnea
Evaluating quality of life in patients with asthma and rhinitis: English adaptation of the rhinasthma questionnaire.
Chen H, Cisternas MG, Katz PP, Omachi TA, Trupin L, Yelin EH, Balmes JR, Blanc PD. Ann Allergy Asthma Immunol. 2011;106(2):110-118.e1.
Risk factors for death in adults with severe asthma.
Omachi TA, Iribarren C, Sarkar U, Tolstykh I, Yelin EH, Katz PP, Blanc PD, Eisner MD. Ann Allergy Asthma Immunol. 2008;101(2):130-6.
Development of disability in chronic obstructive pulmonary disease: beyond lung function.
Eisner MD, Iribarren C, Blanc PD, Yelin EH, Ackerson L, Byl N, Omachi TA, Sidney S, Katz PP. Thorax. 2011 Feb;66(2):108-14.
An international prospective general population-based study of respiratory work disability.
Torén K, Zock JP, Kogevinas M, Plana E, Sunyer J, Radon K, Jarvis D, Kromhout H, d'Errico A, Payo F, Antó JM, Blanc PD. Thorax. 2009 Apr;64(4):339-44.
Predictors of respiratory sickness absence: an international population-based study.
Kim J-L, Blanc PD, Villani S, Oliveri M, Urrutia I, van Sprundel M, Storaas T, Le Moual N, Zock J-P, Torén K. Am J Ind Med 2013; 56:541-49.
Obstructive sleep apnea: a risk factor for work disability.
Omachi TA, Claman DM, Blanc PD, Eisner MD. Sleep. 2009 Jun;32(6):791-8.
Disturbed sleep among COPD patients is longitudinally associated with mortality and adverse COPD outcomes.
Omachi TA, Blanc PD, Claman DM, Chen H, Yelin EH, Julian L, Katz PP. Sleep Med. 2012 May;13(5):476-83.
Occupation and obstructive sleep apnea: a meta-analysis.
Schwartz DA, Vinnikov D, Blanc PD. J Occup Environ Med. 2017;59(6):502-508
Fatigue and sleepiness determine respiratory quality of life among veterans evaluated for sleep apnea.
Vinnikov D, Blanc PD, Alilin A, Zutler M, Holty JC. Health Qual Life Outcomes. 2017 Mar 14;15(1):48.
The Laboratory-based Intermountain Validated Exacerbation (LIVE) score identifies chronic obstructive pulmonary disease patients at high mortality risk.
Blagev DP, Collingridge DS, Rea S, Horne BD, Press VG, Churpek MM, Carey KA, Mularski RA, Zeng S, Arjomandi M. Front Med (Lausanne). 2018 Jun 11;5:173.
Lung volume indices predict morbidity in smokers with preserved spirometry.
Zeng S, Tham A, Bos B, Jin J, Giang B, Arjomandi M. Thorax. 2019 Feb;74(2):114-124.
Stability of frequency of severe chronic obstructive pulmonary disease exacerbations and health care utilization in clinical populations.
Blagev DP, Collingridge DS, Rea S, Press VG, Churpek MM, Carey K, Mularski RA, Zeng S, Arjomandi M. Chronic Obstr Pulm Dis. 2018 Jun 20;5(3):208-220.
Clinical significance of bronchodilator responsiveness evaluated by forced vital capacity in COPD: SPIROMICS cohort analysis.
Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, Woodruff PG, Han MK, Martinez FJ, Hansel N, Wells JM, Ortega VE, Hoffman EA, Doerschuk CM, Kim V, Dransfield MT, Drummond MB, Bowler R, Criner G, Christenson SA, Ronish B, Peters SP, Krishnan JA, Tashkin DP, Cooper CB; NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS).
Int J Chron Obstruct Pulmon Dis. 2019 Dec 20;14:2927-2938.
Laboratory-based Intermountain Validated Exacerbation (LIVE) Score stability in patients with chronic obstructive pulmonary disease.
Blagev DP, Collingridge DS, Rea S, Carey KA, Mularski RA, Zeng S, Arjomandi M, Press VG.
BMJ Open Respir Res. 2020 Feb;7(1):e000450.
Associations among 25-hydroxyvitamin D levels, lung function, and exacerbation outcomes in COPD: an analysis of the SPIROMICS cohort.
Burkes RM, Ceppe AS, Doerschuk CM, Couper D, Hoffman EA, Comellas AP, Barr RG, Krishnan JA, Cooper C, Labaki WW, Ortega VE, Wells JM, Criner GJ, Woodruff PG, Bowler RP, Pirozzi CS, Hansel NN, Wise RA, Brown TT, Drummond MB; SPIROMICS Investigators.Chest. 2020 Apr;157(4):856-865.
Healthcare Costs of Lung Disease
A comprehensive study of the direct and indirect costs of adult asthma.
Cisternas MG, Blanc PD, Yen IH, Katz PP, Earnest G, Eisner MD, Shiboski S, Yelin EH. J Allergy Clin Immunol. 2003;111(6):1212-8.
Risk adjustment for health care financing in chronic disease: What are we missing by failing to account for disease severity?
Omachi TA, Gregorich SE, Eisner MD, Penaloza RA, Tolstykh IV, Yelin EH, Iribarren C, Dudley RA, Blanc PD.Medical Care 2013;51:740-7.
Biomarkers Linked to Respiratory Disease Outcomes
Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency.
Omachi TA, Eisner MD, Rames A, Markovtsova L, Blanc PD. Respir Res. 2011 Mar 23;12:35.
Chest wall shrapnel-induced beryllium-sensitization and associated pulmonary disease.
Fireman E, Bar Shai A, Lerman Y, Topilsky M, Blanc PD, Maier L, Li L, Chandra S, Abraham JM, Fomin I, Aviram G, Abraham JL.
Sarcoidosis Vasc Diffuse Lung Dis Sarcoidosis Vasc Diffuse Lung Dis 2012; 29: 147-150.
Adverse respiratory effects associated with cadmium exposure in small-scale jewellery workshops in India.
Moitra S, Blanc PD, Sahu S. Thorax 2013; 68:565-70.
Thirdhand cigarette smoke in an experimental chamber: evidence of surface deposition of nicotine, nitrosamines and polycyclic aromatic hydrocarbons and de novo formation of NNK.
Schick SF, Farraro KF, Perrino C, Sleiman M, van de Vossenberg G, Trinh MP, Hammond SK, Jenkins BM, Balmes J. Tob Control. 2014;23(2):152-9.
Use of cleaner-burning biomass stoves and airway macrophage black carbon in Malawian women.
Whitehouse AL, Miyashita L, Liu NM, Lesosky M, Flitz G, Ndamala C, Balmes JR, Gordon SB, Mortimer K, Grigg J. Sci Total Environ. 2018; 635:405-411.
Exposure to household air pollution from wood combustion and association with respiratory symptoms and lung function in nonsmoking women: results from the RESPIRE trial, Guatemala.
Pope D, Diaz E, Smith-Sivertsen T, Lie RT, Bakke P, Balmes JR, Smith KR, Bruce NG. Environ Health Perspect. 2015;123(4):285-92.
Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution.
Lawin H, Ayi Fanou L, Hinson V, Wanjiku J, Ukwaja NK, Gordon SB, Fayomi B, Balmes JR, Houngbegnon P, Avokpaho E, Sanni A.
BMC Public Health. 2017 Apr 17;17(1):320.
Biomarkers of exposure to new and emerging tobacco delivery products.
Schick SF, Blount BC, Jacob P Rd, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A.
Am J Physiol Lung Cell Mol Physiol. 2017;313(3):L425-L452.
Airflow limitation classified with the fixed ratio or the lower limit of normal and cause-specific mortality - A prospective study.
Torén K, Andersson M, Olin AC, Blanc PD, Järvholm B. Respir Med. 2018 Nov;144:36-41.
Analytical validation of a novel multi-analyte plasma test for lung nodule characterization.
Trivedi NN, Brown JK, Rubenstein T, Rostykus AD, Fish AL, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Sidhu M, Vuong D, Wang S, Beggs M, Wu AH, Arjomandi M.
Biomed Res Rev. 2018 Dec;2(3):123.
Risk assessment for indeterminate pulmonary nodules using a novel, plasma-protein based biomarker assay.
Trivedi NN, Arjomandi M, Brown JK, Rubenstein T, Rostykus AD, Esposito S, Axler E, Beggs M, Yu H, Carbonell L, Juang A, Kamer S, Patel B, Wang S, Fish AL, Haddad Z, Wu AH. Biomed Res Clin Pract. 2018 Dec;3(4):10.15761/brcp.1000173.
Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS.
Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Paine R 3rd, Peters SP, Rennard SI, Woodruff PG; SPIROMICS Investigators.
Eur Respir J. 2019 Oct 31;54(4):1802214.
The Effects of rare SERPINA1 variants on lung function and emphysema in SPIROMICS.
Ortega VE, Li X, O'Neal WK, Lackey L, Ampleford E, Hawkins GA, Grayeski PJ, Laederach A, Barjaktarevic I, Barr RG, Cooper C, Couper D, Han MK, Kanner RE, Kleerup EC, Martinez FJ, Paine R 3rd, Peters SP, Pirozzi C, Rennard SI, Woodruff PG, Hoffman EA, Meyers DA, Bleecker ER; NHLBI Subpopulations and Intermediate Outcomes Measures in COPD Study (SPIROMICS). Am J Respir Crit Care Med. 2020 Mar 1;201(5):540-554.
Lower PDL1, PDL2, and AXL expression on lung myeloid cells suggests inflammatory bias in smoking and chronic obstructive pulmonary disease.
Vasudevan S, Vásquez JJ, Chen W, Aguilar-Rodriguez B, Niemi EC, Zeng S, Tamaki W, Nakamura MC, Arjomandi M.
Am J Respir Cell Mol Biol. 2020 Dec;63(6):780-793.
Ratio of FEV1/slow vital capacity of < 0.7 is associated with clinical, functional, and radiologic features of obstructive lung disease in smokers with preserved lung function.
Fortis S, Comellas AP, Bhatt SP, Hoffman EA, Han MK, Bhakta NR, Paine R 3rd, Ronish B, Kanner RE, Dransfield M, Hoesterey D, Buhr RG, Barr RG, Dolezal B, Ortega VE, Drummond MB, Arjomandi M, Kaner RJ, Kim V, Curtis JL, Bowler RP, Martinez F, Labaki WW, Cooper CB, O'Neal WK, Criner G, Hansel NN, Krishnan JA, Woodruff P, Couper D, Tashkin D, Barjaktarevic I. Chest. 2021 Jul;160(1):94-103.
Traffic-related air pollution, biomarkers of metabolic dysfunction, oxidative stress, and CC16 in children.
Zhang AL, Balmes JR, Lutzker L, Mann JK, Margolis HG, Tyner T, Holland N, Noth EM, Lurmann F, Hammond SK, Holm SM. J Expo Sci Environ Epidemiol. 2022 Jul;32(4):530-537.
Lung Transplantation
Survival following lung transplantation for silicosis and other occupational lung diseases.
Singer JP, Chen H, Phelan T, Kukreja J, Golden JA, Blanc PD. Occup Med (Lond). 2012 Mar;62(2):134-7.
Development and validation of a lung transplant-specific disability questionnaire.
Singer JP Blanc PD, Dean M, Hays S, Leard L, Kukreja J, Golden J, Katz PP. Thorax 2014; 69:445-50.
Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation.
Singer JP, Diamond JM, Gries CJ, McDonnough J, Blanc PD, et. al. Am J Respir Crit Care Med 2015; 192: 1325-1334.
Lung transplantation for hypersensitivity pneumonitis.
Kern R, Singer J, Koth Laura, Mooney J, Golden J, Hays S, Greenland J, Wolters P, Ghio E, Jones K, Leard L, Kukreja J, Blanc P. Chest 2015; 147:1558-1561.
Effect of lung transplantation on health-related quality of life in the era of the Lung Allocation Score: a U.S. prospective cohort study.
Singer JP, Katz PP, Soong A, Shrestha P, Huang D, Ho J, Mindo M, Greenland JR, Hays SR, Golden J, Kukreja J, Kleinhenz ME, Shah RJ, Blanc PD.
Am J Transplant. 2017; 17(5):1334-1345.
Survival following lung transplantation for artificial stone silicosis relative to idiopathic pulmonary fibrosis.
Rosengarten D, Fox BD, Fireman E, Blanc PD, Rusanov V, Fruchter O, Raviv Y, Shtraichman O, Saute M, Kramer MR.
Am J Ind Med. 2017 Mar;60(3):248-254.
Incidence of and risk factors for skin cancer in organ transplant recipients in the United States.
Garrett GL, Blanc PD, Boscardin J, Lloyd AA, Ahmed RL, Anthony T, Bibee K, Breithaupt A, Cannon J, Chen A, Cheng JY, Chiesa-Fuxench Z, Colegio OR, Curiel-Lewandrowski C, Del Guzzo CA, Disse M, Dowd M, Eilers R Jr, Ortiz AE, Morris C, Golden SK, Graves MS, Griffin JR, Hopkins RS, Huang CC, Bae GH, Jambusaria A, Jennings TA, Jiang SI, Karia PS, Khetarpal S, Kim C, Klintmalm G, Konicke K, Koyfman SA, Lam C, Lee P, Leitenberger JJ, Loh T, Lowenstein S, Madankumar R, Moreau JF, Nijhawan RI, Ochoa S, Olasz EB, Otchere E, Otley C, Oulton J, Patel PH, Patel VA, Prabhu AV, Pugliano-Mauro M, Schmults CD, Schram S, Shih AF, Shin T, Soon S, Soriano T, Srivastava D, Stein JA, Sternhell-Blackwell K, Taylor S, Vidimos A, Wu P, Zajdel N, Zelac D, Arron ST. JAMA Dermatol. 2017 Mar 1;153(3):296-303.
Improvement in patient-reported outcomes after lung transplantation is not impacted by the use of extracorporeal membrane oxygenation as a bridge to transplantation.
Kolaitis NA, Soong A, Shrestha P, Zhuo H, Neuhaus J, Katz PP, Greenland JR, Golden J, Leard LE, Shah RJ, Hays SR, Kukreja J, Kleinhenz ME, Blanc PD, Singer JP.
J Thorac Cardiovasc Surg. 2018 Jul;156(1):440-448.e2.
Frailty trajectories in adult lung transplantation: A cohort study.
Venado A, McCulloch C, Greenland JR, Katz P, Soong A, Shrestha P, Hays S, Golden J, Shah R, Leard LE, Kleinhenz ME, Kukreja J, Zablotska L, Allen IE, Covinsky K, Blanc P, Singer JP.J Heart Lung Transplant. 2019 Jul;38(7):699-707.
Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients.
Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, Blanc PD, Singer JP. Am J Health Syst Pharm. 2019 Dec 2;76(24):2019-2027.
Frailty after lung transplantation is associated with impaired health-related quality of life and mortality.
Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. Thorax. 2020 Aug;75(8):669-678.
Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression.
Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP.
Am J Transplant. 2021 Feb;21(2):815-824.
Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction.
Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden JA, Venado A, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Kukreja J, Blanc PD, Smith PJ, Singer JP. Thorax. 2022 Sep;77(9):891-899.
Quality of Life and Patient Perceived Health Status and Medication Effects in Pulmonary Hypertension
Comparison of cardiac and pulmonary-specific quality-of-life measures in pulmonary arterial hypertension.
Chen H, De Marco T, Kobashigawa EA, Katz PP, Chang VW, Blanc PD. Eur Respir J. 2011 Sep;38(3):608-16.
Effects of commercial air travel on patients with pulmonary hypertension air travel and pulmonary hypertension.
Roubinian N, Elliott CG, Barnett CF, Blanc PD, Chen J, De Marco T, Chen H. Chest. 2012 Oct;142(4):885-92.
Occupational and Environmental Disorders and Function of the Upper airway
Nasal physiological reactivity of subjects with nonallergic rhinitis to cold air provocation: a pilot comparison of subgroups.
Shusterman DJ, Tilles SA. Am J Rhinol Allergy. 2009 Sep-Oct;23(5):475-9.
Pilot evaluation of the nasal nitric oxide response to humming as an index of osteomeatal patency.
Shusterman DJ, Weaver EM, Goldberg AN, Schick SF, Wong HH, Balmes JR. Am J Rhinol Allergy. 2012 Mar-Apr;26(2):123-6.
Occupational rhinitis and other work-related upper respiratory tract conditions.
Zhao YA, Shusterman D. Clin Chest Med. 2012 Dec;33(4):637-47.
Thirty minute-exposure to aged cigarette smoke increases nasal congestion in nonsmokers.
Schick SF, van den Vossenberg G, Luo A, Whitlatch A, Jacob P 3rd, Balmes J, Shusterman D. J Toxicol Environ Health A. 2013;76(10):601-13
Occupational irritant and allergic rhinitis.
Shusterman D. Curr Allergy Asthma Rep 2014; 14:425.
The nasal nitric oxide response to external acoustic energy: A pilot study of sampling dynamics.
Shusterman D. Sinusitis 2015; 1(1):13-23.
Nonallergic rhinitis: Environmental determinants.
Shusterman D. Immunol All Clin NA 2016; 36(2):379-399.
Role of the Allergist-Immunologist and Upper Airway Allergy in Sleep-Disordered Breathing.
Shusterman D, Baroody FM, Craig T, Friedlander S, Nsouli T, Silverman B; American Academy of Allergy, Asthma & Immunology's Rhinitis, Rhinosinusitis and Ocular Allergy Committee Work Group on Rhinitis and Sleep-disordered Breathing. J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):628-639.
Occupational rhinitis and occupational asthma: Association or progression?
Balogun RA, Siracusa A, Shusterman D. Am J Ind Med. 2018;61(4):293-307.
Impact of rhinitis on work productivity: a systematic review.
Vandenplas O, Vinnikov D, Blanc PD, Agache I, Bachert C, Bewick M, Cardell LO, Cullinan P, Demoly P, Descatha A, Fonseca J, Haahtela T, Hellings PW, Jamart J, Jantunen J, Kalayci Ö, Price D, Samolinski B, Sastre J, Tian L, Valero AL, Zhang X, Bousquet J. J Allergy Clin Immunol Pract. 2018; 6(4):1274-1286.e9.
Nasal trigeminal perception of two representative microbial volatile organic compounds
(MVOCs): 1-Octen-3-ol and 3-octanol – a pilot study. Shusterman D, Wang P, Kumagai K. Chem Percept 2018; 11:27–34.
FMRI correlates of olfactory processing in typically-developing school-aged children.
Kleinhans NM, Reilly M, Blake M, Greco G, Sweigert J, Davis GE, Velasquez F,Reitz F, Shusterman D, Dager SR. Psychiatry Res Neuroimaging. 2019;283:67-76.
A simplified technique for evaluating nasal mucociliary clearance via saccharin transit time.
Shusterman D. Int Forum Allergy Rhinol. 2020 Apr;10(4):572-574.
Association of allergic rhinitis with change in nasal congestion in new continuous positive airway pressure users.
Skirko JR, James KT, Shusterman DJ, Weaver EM. JAMA Otolaryngol Head Neck Surg. 2020 Jun 1;146(6):523-529.
Computational modeling of nasal nitric oxide flux from the paranasal sinuses: Validation against human experiment.
Spector BM, Shusterman DJ, Goldberg AN, Weaver EM, Farag AA, Otto BA, Zhao K. Comput Biol Med. 2021 Jul 31;136:104723.
Use of computational fluid dynamics (CFD) to model observed nasal nitric oxide levels in human subjects.
Shusterman DJ, Spector BM, Goldberg AN, Weaver EM, Otto BA, Zhao K. Int Forum Allergy Rhinol. 2022 May;12(5):735-743.
Nasal nitric oxide flux from the paranasal sinuses.
Spector BM, Shusterman DJ, Zhao K. Curr Opin Allergy Clin Immunol. 2023 Feb 1;23(1):22-28.
Cognitive Function and Depression in Obstructive Lung Disease
Onset of depressive symptoms among adults with asthma: results from a longitudinal observational cohort.
Katz PP, Morris A, Julian L, Omachi T, Yelin EH, Eisner MD, Blanc PD. Prim Care Respir J. 2010 Sep;19(3):223-30.
COPD and cognitive impairment: the role of hypoxemia and oxygen therapy.
Thakur N, Blanc PD, Julian LJ, Yelin EH, Katz PP, Sidney S, Iribarren C, Eisner MD. Int J Chron Obstruct Pulmon Dis. 2010 Sep 7;5:263-9.
The role of social support in anxiety for persons with COPD.
DiNicola G, Julian L, Gregorich SE, Blanc PD, Katz PP. J Psychosom Res 2013; 74:110-5.
Silica, Silicosis and Other Pneumoconioses
Survival following lung transplantation for silicosis and other occupational lung diseases.
Singer JP, Chen H, Phelan T, Kukreja J, Golden JA, Blanc PD. Occup Med (Lond). 2012 Mar;62(2):134-7.
Artificial stone silicosis: Disease resurgence among artificial stone workers.
Kramer MR, Blanc PD, Fireman E, Amital A Guber A, Rhahman NA, Shitrit D. Chest 2012; 142:419-24
Outbreak of autoimmune disease in silicosis linked to artificial stone.
Shtraichman O, Blanc PD, Ollech JE, Fridel L, Fuks L, Fireman E, Kramer MR. Occup Med (London) 2015;65:444-50.
“Acute” Silicosis in the 1930 Johannesburg International Silicosis Conference and in its aftermath: Controversies over a distinct entity later recognized as silicoproteinosis.
Blanc PD. Am J Ind Med 2015; 2015;58 (Suppl 1):39-47.
Prospective risk of rheumatologic disease associated with occupational exposure in a cohort of male construction workers.
Blanc PD, Järvholm B, Torén K. Am J Med 2015; 128:1094-1101.
EBUS-TBNA is sufficient for successful diagnosis of silicosis with mediastinal lymphadenopathy.
Shitrit D, Adir Y, Avriel A, King D, Epstein Shochet G, Guber A, Schnaer S, Kassirer M, Blanc PD, Abramovich A. Lung. 2018; 196(4):441-445.
Severe silicosis in engineered stone fabrication workers - California, Colorado, Texas, and Washington, 2017-2019.
Rose C, Heinzerling A, Patel K, Sack C, Wolff J, Zell-Baran L, Weissman D, Hall E, Sooriash R, McCarthy RB, Bojes H, Korotzer B, Flattery J, Weinberg JL, Potocko J, Jones KD, Reeb-Whitaker CK, Reul NK, LaSee CR, Materna BL, Raghu G, Harrison R. MMWR Morb Mortal Wkly Rep. 2019 Sep 27;68(38):813-818.
Early radiographic pneumoconiosis is associated with impaired exercise gas exchange among coal miners with normal resting spirometry.
Gandhi SA, Cohen RA, Blanc PD, Go LHT. Am J Ind Med. 2021 Jun;64(6):453-461.
Radiographic screening reveals high burden of silicosis among workers at an engineered stone countertop fabrication facility in California.
Heinzerling A, Cummings KJ, Flattery J, Weinberg JL, Materna B, Harrison R. Am J Respir Crit Care Med. 2021 Mar 15;203(6):764-766.
Self-reported silica exposures and workplace protections among engineered stone fabrication workers in California.
Spiegel A, Cummings KJ, Flattery J, Harrison R, Heinzerling A. Am J Ind Med. 2022 Dec;65(12):1022-1024.
Elevated exposures to respirable crystalline silica among engineered stone fabrication workers in California, January 2019-February 2020.
Surasi K, Ballen B, Weinberg JL, Materna BL, Harrison R, Cummings KJ, Heinzerling A. Am J Ind Med. 2022 Sep;65(9):701-707.
Assessment of Risk of Rheumatoid Arthritis Among Underground Hard Rock and Other Mining Industry Workers in Colorado, New Mexico, and Utah.
Blanc PD, Trupin L, Yelin EH, Schmajuk G. JAMA Netw Open. 2022 Oct 3;5(10):e2236738.
Colinet-Caplan Syndrome: History of an outbreak of autoimmune disease in scouring powder workers.
Ronsmans S, Blanc PD. Ann Intern Med. 2023 Feb;176(2):260-265.
Novel or Emerging Exposure Scenarios or Disease Outcomes
Five-year function observations and associations with a smoking ban among healthy miners at high altitude (4000 m).
Vinnikov D, Blanc PD, Brimkulov N, Redding-Jones R. J Occup Environ Med 2013; 55:1422-5.
Fatalities due to dichloromethane in paint strippers: a continuing problem.
Macisaac J, Harrison R, Krishnaswami J, McNary J, Suchard J, Boysen-Osborn M, Cierpich H, Styles L, Shusterman D. Am J Ind Med. 2013 Aug;56(8):907-10
Airflow obstruction among street vendors refilling cigarette lighter with liquefied petroleum gas. Int J
Moitra S, Blanc PD, Brashier BB. Int J Tuberc Lung Dis 2014; 18:1126-31
Healthcare worker exposures to the antibacterial agent triclosan.
MacIsaac JK, Gerona R, Blanc PD, Apatira L, Friesen M, Coppolino M, Janssen S. J Occup Environ Med 2014; 56:834-39.
Effects of woodsmoke exposure on airway inflammation in rural Guatemalan women.
Guarnieri MJ, Diaz JV, Basu C, Diaz A, Pope D, Smith KR, Smith-Sivertsen T, Bruce N, Solomon C, McCracken J, Balmes JR. PLoS One. 2014 Mar 13;9(3):e88455
Coccidioidomycosis among workers constructing solar power farms, California, USA, 2011-2014.
Wilken JA, Sondermeyer G, Shusterman D, McNary J, Vugia DJ, McDowell A, Borenstein P, Gilliss D, Ancock B, Prudhomme J, Gold D, Windham GC, Lee L, Materna BL.
Emerg Infect Dis 2015; 21(11):1997-2005.
Fungal contamination of the respiratory tract and associated respiratory impairment among saw-mill workers in India.
Adhikari A, Sahu S, Bandyopadhyay A, Blanc PD, Moitra S. ERJ Open Research Oct 2015; 1(2)
Occupational HIV transmission among male adult film performers - multiple atates, 2014.
Wilken JA, Ried C, Rickett P, Arno JN, Mendez Y, Harrison RJ, Wohlfeiler D, Bauer HM, Joyce MP, Switzer WM, Heneine W, Shankar A, Mark KE
MMWR Morb Mortal Wkly Rep. 2016 Feb 12;65(5):110-4.
Sudden deaths among oil and gas extraction workers resulting from oxygen deficiency and inhalation of hydrocarbon gases and vapors - United States, January 2010-March 2015.
Harrison RJ, Retzer K, Kosnett MJ, Hodgson M, Jordan T, Ridl S, Kiefer M. MMWR Morb Mortal Wkly Rep. 2016 Jan 15;65(1):6-9.
Is smoking a predictor for acute mountain sickness? Findings from a meta-analysis.
Vinnikov D, Blanc PD, Steinmaus C. Nicotine Tob Res; 2016, 18:1509-1516.
Dust exposure and coccidioidomycosis prevention among solar power farm Construction workers in California.
Sondermeyer Cooksey GL, Wilken JA, McNary J, Gilliss D, Shusterman D, Materna BL, Vugia DJ. Am J Public Health. 2017;107(8):1296-1303.
Prevalence of arthritis and rheumatoid arthritis in coal mining counties of the United States.
Schmajuk G, Trupin L, Yelin E, Blanc PD. Arthritis Care Res (Hoboken). 2019 Sep;71(9):1209-1215.
Characterization of carbon monoxide exposure during Hurricane Sandy and subsequent nor'easter.
Schnall A, Law R, Heinzerling A, Sircar K, Damon S, Yip F, Schier J, Bayleyegn T, Wolkin A. Disaster Med Public Health Prep. 2017 Oct;11(5):562-567.
Bismuth subgallate toxicity in the age of online supplement use.
Sampognaro P, Vo KT, Richie M, Blanc PD, Keenan K. Neurologist. 2017 Nov;22(6):237-240.
The early history of manganese and the recognition of its neurotoxicity, 1837-1936.
Blanc PD. Neurotoxicology. 2018 Jan;64:5-11.
Lead exposure in the special operations shooter: How to prevent cognitive decline and permanent disability.
Brandon JW, Solarczyk JK, Durrani TS. J Spec Oper Med. 2018; 18:81-7
Pulmonary toxicity associated with pomalidomide.
Gajic S, Callahan EC, Brown JK, Elicker B, Ley B, Blanc PD. Int J Tuberc Lung Dis. 2018 Nov 1;22(11):1383-1386.
Measurement of heating coil temperature for e-cigarettes with a "top-coil" clearomizer.
Chen W, Wang P, Ito K, Fowles J, Shusterman D, Jaques PA, Kumagai K. PLoS One. 2018; 13(4):e0195925.
Notes from the field: toxic leukoencephalopathy associated with tianeptine misuse - California, 2017.
Goodnough R, Li K, Fouladkou F, Lynch KL, Shah M, Smollin CG, Blanc PD. MMWR Morb Mortal Wkly Rep. 2018 Jul 13;67(27):769-770.
Nanotechnology and Health.
Fischman M, Murashov V, Borak J, Seward J; ACOEM Task Force on Nanotechnology and Health. J Occup Environ Med. 2019 Mar;61(3):e95-e98.
Night and rotational work exposure within the last 12 months and risk of incident hypertension.
Ferguson JM, Costello S, Neophytou AM, Balmes JR, Bradshaw PT, Cullen MR, Eisen EA. Scand J Work Environ Health. 2019 May 1;45(3):256-266.
Solvent-based paint and varnish removers: a focused toxicologic review of existing and alternative constituents.
Durrani T, Clapp R, Harrison R, Shusterman D. J Appl Toxicol. 2020 Oct;40(10):1325-1341.
Risk factors for occupational heat-related illness among California workers, 2000-2017.
Heinzerling A, Laws RL, Frederick M, Jackson R, Windham G, Materna B, Harrison R. Am J Ind Med. 2020 Dec;63(12):1145-1154.
Notes from the field: methylmercury toxicity from a skin lightening cream obtained from Mexico - California, 2019.
Mudan A, Copan L, Wang R, Pugh A, Lebin J, Barreau T, Jones RL, Ghosal S, Lee M, Albertson T, Jarrett JM, Lee J, Betting D, Ward CD, De Leon Salazar A, Smollin CG, Blanc PD. MMWR Morb Mortal Wkly Rep. 2019 Dec 20;68(50):1166-1167.
Assessment of methylene chloride-related fatalities in the United States, 1980-2018.
Hoang A, Fagan K, Cannon DL, Rayasam SDG, Harrison R, Shusterman D, Singla V. JAMA Intern Med. 2021 Jun 1;181(6):797-805.
Gamma-butyrolactone overdose potentially complicated by co-ingestion of industrial solvent N-methyl-2-pyrrolidone.
Melamed J, Gerona R, Blanc PD, Takamoto P, Conner S, Goodnough R. J Anal Toxicol. 2021 Mar 12;45(3):322-324.
Fractional exhaled NO in a metalworking occupational cohort.
Vinnikov D, Tulekov Z, Blanc PD. Int Arch Occup Environ Health. 2022 Apr;95(3):701-708.
Exposure to respirable dust among workers fabricating aluminium trihydroxide-containing synthetic countertops.
Vinnikov D, Blanc PD, Raushanova A, Beisbekova A, Abraham JL, Zlobina Y. Sci Rep. 2021 Oct 27;11(1):21219.
Pneumococcal pneumonia on the job: Uncovering the past story of occupational exposure to metal fumes and dust.
Torén K, Naidoo RN, Blanc PD. Am J Ind Med. 2022 Jul;65(7):517-524.
Occupational exposures in nontuberculous mycobacterial pulmonary disease.
Blanc PD, Balmes JR, Redlich C. Chest. 2022 Aug;162(2):e106-e107.
Cumulative occupational exposure to inorganic dust and fumes and invasive pneumococcal disease with pneumonia.
Torén K, Blanc PD, Naidoo R, Murgia N, Stockfelt L, Schiöler L. Int Arch Occup Environ Health. 2022 Oct;95(8):1797-1804.
Advancing the science on chemical classes.
Maffini MV, Rayasam SDG, Axelrad DA, Birnbaum LS, Cooper C, Franjevic S, MacRoy PM, Nachman KE, Patisaul HB, Rodgers KM, Rossi MS, Schettler T, Solomon GM, Woodruff TJ. Environ Health. 2023 Jan 12;21(Suppl 1):120.
A science-based agenda for health-protective chemical assessments and decisions: overview and consensus statement.
Woodruff TJ, Rayasam SDG, Axelrad DA, Koman PD, Chartres N, Bennett DH, Birnbaum LS, Brown P, Carignan CC, Cooper C, Cranor CF, Diamond ML, Franjevic S, Gartner EC, Hattis D, Hauser R, Heiger-Bernays W, Joglekar R, Lam J, Levy JI, MacRoy PM, Maffini MV, Marquez EC, Morello-Frosch R, Nachman KE, Nielsen GH, Oksas C, Abrahamsson DP, Patisaul HB, Patton S, Robinson JF, Rodgers KM, Rossi MS, Rudel RA, Sass JB, Sathyanarayana S, Schettler T, Shaffer RM, Shamasunder B, Shepard PM, Shrader-Frechette K, Solomon GM, Subra WA, Vandenberg LN, Varshavsky JR, White RF, Zarker K, Zeise L. Environ Health. 2023 Jan 12;21(Suppl 1):132.
Notes from the Field: Harmful algal bloom affecting private drinking water intakes - Clear Lake, California, June-November 2021.
Solomon GM, Stanton B, Ryan S, Little A, Carpenter C, Paulukonis S. MMWR Morb Mortal Wkly Rep. 2022 Oct 14;71(41):1306-1307.
Occupational Health Policy and Promotion
Work related injuries in Qatar: a framework for prevention and control.
Mehmood A, Maung Z, Consunji RJ, El-Menyar A, Peralta R, Al-Thani H, Hyder AA. J Occup Med Toxicol. 2018 Sep 5;13:29.
Into ploughshares: forging effective surveillance for work-related lung disease.
Reynolds CJ, Blanc P. Occup Environ Med. 2019 Nov;76(11):783-784.
What has been done will be done again.
Blanc PD. Respirology. 2019 Dec;24(12):1125-1126.
The heat death line: proposed heat index alert threshold for preventing heat-related fatalities in the civilian workforce.
Maung Z, Tustin AW. New Solut. 2020 Aug;30(2):138-145.
Elastomeric respirators for all healthcare workers.
Brosseau LM, Jones RM, Harrison R. Am J Infect Control. 2021 Mar;49(3):405-406.
History of Work-related Diseases as a tool to protect the health of workers.
Naidoo RN, Blanc PD, Torén K. Ind Health. 2021 Sep 9;59(4):204-203.
Respiratory Protection for the Nation: A report from the National Academies of Sciences, Engineering, and Medicine.
Samet JM, Holm SM, Jayaraman S. JAMA. 2022 Mar 15;327(11):1023-1024.
Safe patient handling legislation and musculoskeletal disorders among California healthcare workers: Analysis of workers' compensation data, 2007-2016.
Lee SJ, Lee JH, Harrison R. Am J Ind Med. 2022 Jul;65(7):589-603.
Differences in hospitals' workplace violence incident reporting practices: A mixed methods study.
Odes R, Chapman S, Ackerman S, Harrison R, Hong O. Policy Polit Nurs Pract. 2022 May;23(2):98-108.
Development of a data visualization tool for occupational exposure to chemicals of concern for breast cancer among California working women, 2010-2014.
Beckman S, Silver E, Weinberg JL, Hurley S, Frederick M, Chan J, Reynolds P, Harrison R. New Solut. 2022 Feb;31(4):400-412.
Work-related Factors in Upper and Lower Limb Disorders
1st place, PREMUS best paper competition: workplace and individual factors in wrist tendinosis among blue-collar workers--the San Francisco study.
Harris C, Eisen EA, Goldberg R, Krause N, Rempel D. Scand J Work Environ Health. 2011 Mar;37(2):85-98.
Effort-reward imbalance and one-year change in neck-shoulder and upper extremity pain among call center computer operators.
Krause N, Burgel B, Rempel D. Scand J Work Environ Health. 2010 Jan;36(1):42-53.
Follow-up of neck and shoulder pain among sewing machine operators: The Los Angeles garment study.
Wang PC, Harrison RJ, Yu F, Rempel DM, Ritz BR. Am J Ind Med. 2010 Apr;53(4):352-60.
Meta-analysis: association between wrist posture and carpal tunnel syndrome among workers.
You D, Smith AH, Rempel D. Saf Health Work. 2014 Mar;5(1):27-31
Personal and workplace psychosocial risk factors for carpal tunnel syndrome: a pooled study cohort.
Harris-Adamson C, Eisen EA, Dale AM, Evanoff B, Hegmann KT, Thiese M, Kapellusch J, Garg A, Burt S, Bao S, Silverstein B, Gerr F, Merlino L, and Rempel D.
Occup Environ Med. 2013;70(8):529-37.
The impact of posture on wrist tendinosis among blue-collar workers − the San Francisco study.
Harris-Adamson C, Eisen EA, Goldberg R, You D, and Rempel D. Human Factors. 2014;56(1):143-150.
Personal and workplace factors and median nerve function in a pooled study of 2396 US workers.
Rempel D, Gerr F, Harris-Adamson C, Hegmann KT, Thiese MS, Eisen EA, Kapellusch J, Garg A, Burt S, Bao S, Silverstein B, Merlino L, Dale AM, Evanoff B.
J Occupational and Environmental Medicine. 2015;57(1):98-104.
Biomechanical risk factors for carpal tunnel syndrome: a pooled study of 2474 workers.
Harris-Adamson C, Eisen EA, Kapellusch J, Garg A, Hegmann KT, Thiese MS, Dale AM, Evanoff B, Burt S, Bao S, Silverstein B, Merlino L, Gerr F, Rempel D.
Occup Environ Med 2015;72(1):33-41.
Lateral epicondylitis: New evidence for work relatedness.
Descatha A, Dale AM, Silverstein BA, Roquelaure Y, Rempel D. Joint Bone Spine 2015; 82(1):5-7.
Effectiveness of workplace interventions in the prevention of upper extremity musculoskeletal disorders and symptoms: an update of the evidence.
Van Eerd D, Munhall C, Irvin E, Rempel D, Brewer S, van der Beek AJ, Dennerlein JT, Tullar J, Skivington K, Pinion C, Amick B.
Occupational and Environmental Medicine 2016; 73(1):62-70
Biomechanical and psychosocial exposures are independent risk factors for carpal tunnel syndrome: assessment of confounding using causal diagrams.
Harris-Adamson C, Eisen EA, Neophytou A, Kapellusch J, Garg A, Hegmann KT, Thiese MS, Dale AM, Evanoff B, Bao S, Silverstein B, Gerr F, Burt S, Rempel D.
Occup Environ Med. 2016;73(11):727-734.
A new test bench system for hammer drills: validation for handle vibration.
Rempel D, Barr A, Antonucci A. Int J Ind Ergon. 2017; 62:17-20.
Incident CTS in a large pooled cohort study: associations obtained by a Job Exposure Matrix versus associations obtained from observed exposures.
Dale AM, Ekenga CC, Buckner-Petty S, Merlino L, Thiese MS, Bao S, Meyers AR, Harris-Adamson C, Kapellusch J, Eisen EA, Gerr F, Hegmann KT, Silverstein B, Garg A, Rempel D, Zeringue A, Evanoff BA. Occup Environ Med. 2018;75(7):501-506.
Shoulder injury related to vaccine administration (SIRVA): An occupational case report.
Shahbaz M, Blanc PD, Domeracki SJ, Guntur S. Workplace Health Saf. 2019;67:501-50
Off the courts: occupational "Tennis Leg".
Domeracki SJ, Landman Z, Blanc PD, Guntur S. Workplace Health Saf. 2019 Jan;67(1):5-8.
Modeling the effect of the 2018 Revised ACGIH Hand Activity Threshold Limit Value (TLV) at reducing risk for carpal tunnel syndrome
Yung M, Dale AM, Kapellusch J, Bao S, Harris C, Meyers A, Hegmann KT, Rempel DM, Evanoff B. Journal of Occupational & Environmental Hygiene. 2019;16(9): 628-633.
Hand posture and force estimation using surface electromyography and an artificial neural network.
Wang M, Zhao C, Barr A, Fan H, Yu S, Kapellusch J, Harris Adamson C. Hum Factors. 2021 May 18:187208211016695.
Biomechanical risk factors associated with distal upper extremity musculoskeletal disorders in endoscopists performing colonoscopy.
Shergill AK, Rempel D, Barr A, Lee D, Pereira A, Hsieh CM, McQuaid K, Harris-Adamson C. Gastrointest Endosc. 2021 Mar;93(3):704-711.e3.
Occupational risk factors for work disability following carpal tunnel syndrome: a pooled prospective study.
Harris-Adamson C, Eisen EA, Kapellusch J, Hegmann KT, Thiese MS, Dale AM, Evanoff B, Meyers AR, Bao S, Gerr F, Krause N, Rempel D. Occup Environ Med. 2022 Jul;79(7):442-451.
The association between forceful hand exertions and musculoskeletal disorders of the neck and shoulder: A prospective cohort study of US manufacturing workers.
Zimbalist A, Rempel D, Feng L, Harris-Adamson C. J Occup Environ Med. 2022 Oct 1;64(10):e613-e621.
Comparison of the observer, single-frame video and computer vision hand activity levels.
Radwin RG, Hu YH, Akkas O, Bao S, Harris-Adamson C, Lin JH, Meyers AR, Rempel D. Ergonomics. 2022 Oct 26:1-10.
Other Ergonomic Assessments and Interventions
The effects of periodontal curette handle weight and diameter on arm pain: a four-month randomized controlled trial.
Rempel D, Lee DL, Dawson K, Loomer P. J Am Dent Assoc. 2012;143(10):1105-13.
Field evaluation of a modified intervention for overhead drilling.
Rempel D, Star D, Barr A, Blanco MM, Janowitz I. J Occup Environ Hyg. 2010;7(4):194-202.
A randomized controlled trial evaluating the effects of new task chairs on shoulder and neck pain among sewing machine operators: the Los Angeles garment study.
Rempel DM, Wang PC, Janowitz I, Harrison RJ, Yu F, Ritz BR. Spine (Phila Pa 1976). 2007 Apr 20;32(9):931-8.
Holding a tablet computer with one hand: effect of tablet design features on biomechanics and subjective usability among users with small hands.
Pereira A, Miller T, Huang YM, Odell D, Rempel D. Ergonomics. 2013;56(9):1363-75
Effect of handle design on pallet jack operations.
Harris-Adamson C. and Lin J. Ergonomics in Design: The quarterly of Human Factors Applications. 2013;21(2):15-21.
The design of gestures for human-computer interaction: Lessons from sign language interpreters.
Rempel D, Lee DL, Camilleri M. International Journal of Human-Computer Studies 2015; 72(10-11):728-735.
A user developed 3D hand gesture set for human-computer interaction.
Pereira A, Wachs JP, Park K, Rempel D. Human Factors 2015; 57(4):607-621.
A universal rig for supporting large hammer drills: Reduced injury risk and improved productivity.
Rempel D, Barr A. Safety Science 2015; 78:20-24.
In vivo flexor tendon forces generated during different rehabilitation exercises.
Edsfeldt S, Rempel D, Kursa K, Diao E, Lattanza L. J Hand Surg (Europe) 2015; 40(7):705-10.
Mind the gap: The effect of keyboard key gap and pitch on typing speed, accuracy, and usability, Part 3.
Madison H, Pereira A, Korshoj, M, Taylor L, Barr A, Rempel D. Human Factors 2015; 57(7):1188-1194.
Ergonomic evaluation of standard and alternative pallet jack handles.
Harris-Adamson C, Mielke A, Xu X, Lin J. International Journal of Industrial Ergonomics. 2016; 54:113-119.
Ergonomic evaluation of an alternative tool for cake decorating.
Harris-Adamson C, Chen B, Janowitz I, Rempel D. International Journal of Industrial Ergonomics. 2017; 57:63-67.
Measuring exertion time, duty cycle and hand activity level for industrial tasks using computer vision.
Akkas O, Lee CH, Hu YH, Harris Adamson C, Rempel D, Radwin RG. Ergonomics. 2017; 60(12):1730-1738.
Sit-stand workstations and impact on low back discomfort: a systematic review and meta-analysis.
Agarwal S, Steinmaus C, Harris-Adamson C. Ergonomics. 2018; 61(4):538-552.
Ergonomic rubber tapping knife relieves symptoms of carpal tunnel syndrome among rubber tappers.
Pramchoo W, Geater AF, Harris Adamson C, Tantrakulwanich B. International Journal of Industrial Ergonomics. 2018;68: 65–72.
Impact of California's safe patient handling legislation on musculoskeletal injury prevention among nurses.
Lee SJ, Lee JH, Harrison R. Am J Ind Med. 2019 Jan;62(1):50-58.
The design of hand gestures for selecting virtual objects
Lin J, Harris-Adamson C & Rempel D. International Journal of Human–Computer Interaction, 2019; 35(18): 1729-1735.
The ergonomic impact of a mattress lift tool and bottom sheet type on hotel room cleaners while making beds
Harris-Adamson C, Lam E, Tong AD, Hill S, Smith A. Applied Ergonomics. 2019; 81:102880.
Design of finger gestures for locomotion in virtual reality.
Huang R, Harris Adamson C, Odell D, Rempel D. Virtual Reality & Intelligent Hardware. 2019; 1(1): 1-9.
Experimental evaluation of shoulder-support exoskeleton for overhead work: Influences of peak torque, amplitude, tasks and tool mass.
Van Engelhoven L, Poon N, Kazerooni H, Rempel D, Barr A, Harris-Adamson C. IISE Transactions on Occupational Ergonomics and Human Factors. 2019; 1-14.
Potential of exoskeleton technologies to enhance safety, health, and performance in construction: industry perspectives and future research directions.
Kim, S., Moore, A., Srinivasan, D., Akanmu, A., Barr, A., Harris-Adamson, C., Rempel, D.M. and Nussbaum, M.A.
IISE Transactions on Occupational Ergonomics and Human Factors. 2019; 1-7.
The impact of heavy load carrying on musculoskeletal pain and disability among women in Shinyanga Region, Tanzania.
Kadota JL, McCoy SI, Bates MN, Mnyippembe A, Njau PF, Prata N, Harris-Adamson C. Ann Glob Health. 2020 Feb 21;86(1):17.
Heavy load carrying and symptoms of pelvic organ prolapse among women in Tanzania and Nepal: an exploratory study.
Koyuncu A, Kadota JL, Mnyippembe A, Njau PF, Sijali TR, McCoy SI, Bates MN, Harris-Adamson C, Prata N. Int J Environ Res Public Health. 2021 Jan 31;18(3):1279.
Endoscopist injury: shifting our focus to interventions.
Harris-Adamson C, Shergill AK. Gastrointest Endosc. 2021 Aug;94(2):260-262.
Analysis of the external acoustic meatus for ergonomic design: part II - anthropometric variations of the external acoustic meatus by sex, age and side in Chinese population.
Fan H, Yu S, Wang M, Li M, Zhao X, Ren Y, Zhang S, Chen D, Harris Adamson C. Ergonomics. 2021 May;64(5):657-670.
Analysis of the external acoustic meatus for ergonomic design: part I - measurement of the external acoustic meatus using casting, scanning and rapid estimation approaches.
Fan H, Yu S, Wang M, Li M, Chu J, Yan Y, Zhang S, Chen D, Harris-Adamson C. Ergonomics. 2021 May;64(5):640-656.
Postural strategies among office workers during a prolonged sitting bout.
Arippa F, Nguyen A, Pau M, Harris-Adamson C. Appl Ergon. 2022 Jul;102:103723.
Assessment of cardiovascular load among hotel room cleaners.
Dinh-Dang D, Khafagy A, Krause N, Harris-Adamson C. Appl Ergon. 2023 Jan;106:103886.
Epidemiology of Neurodegenerative Diseases
Occupation and parkinsonism in three movement disorders clinics.
Goldman SM, Tanner CM, Olanow CW, Watts RL, Field RD, Langston JW. Neurology. 65(9):1430-5, 2005.
Consensus statement: Parkinson’s disease and the environment.
Bronstein J, Carvey P, Chen H, Cory-Slechta D, DiMonte D, Duda J, English P, Goldman S, et. al. Environmental Health Perspectives. 117(1):117-21, 2009.
Rotenone, paraquat and Parkinson’s disease.
Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, et. al. Environmental Health Perspectives.2011; 119:866-872, 2011.
Solvent exposures and Parkinson Disease risk in twins.
Goldman SM, Quinlan PJ, Ross GW, Marras C, Meng C, Bhudhikanok GS, Comyns K, Korell M, Chade AR, Kasten M, Priestley B, Chou KL, Fernandez HH, Cambi F, Langston JW, Tanner CM. Annals of Neurology, 71(6),776-784, 2012.
Genetic modification of the association of paraquat and Parkinson’s Disease.
Goldman SM, Kamel F, Ross GW, et. al. Movement Disorders. 27(13):1652-1658, 2012.
Environmental toxins and Parkinson’s Disease.
Goldman SM. Annual Review of Pharmacology and Toxicology. 54:141-64, 2014.
The disease intersection of susceptibility and exposure: chemical exposures and neurodegenerative disease risk.
Tanner CM, Goldman SM, Ross GW, Grate SJ. Alzheimer’s and Dementia. 2014 Jun;10(3S):S213-S225.
Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson’s disease.
Furlong M, Tanner CM, Goldman SM, et. al. Environment International. 2014, Nov 21;75C:144-150.
Dietary fat intake, pesticide use, and Parkinson's disease.
Kamel F, Goldman SM, Umbach DM, Chen H, Richardson G, Barber MR, Meng C, Marras C, Korell M, Kasten M, Hoppin JA, Comyns K, Chade A, Blair A, Bhudhikanok GS, Webster Ross G, William Langston J, Sandler DP, Tanner CM. Parkinsonism Relat Disord. 2014; 20(1):82-7.
Head injury, alpha-synuclein Rep1 and Parkinson's Disease: a meta-analytic view of gene-environment interaction.
Goldman SM, Umbach DM, Kamel F, Tanner CM. Eur J Neurol, 2015;22(7):e75.
Heart rate variability in leucine-rich repeat kinase 2-associated Parkinson's disease.
Visanji NP, Bhudhikanok GS, Mestre TA, Ghate T, Udupa K, AlDakheel A, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Faust-Socher A, Kim S, Azhu Valappil R, Kausar F, Rogaeva E, William Langston J, Tanner CM, Schüle B, Lang AE, Goldman SM, Marras C. Mov Disord. 2017;32(4):610-614.
The Microbiome in neurodegenerative disease.
Brown E, Tanner CM, Goldman SM. Curr Geriatric Reports. 2018;7:81-91.
Excessive daytime sleepiness, objective napping and 11-year risk of Parkinson’s disease in older men.
Leng Y, Goldman SM, Cawthon PM, Stone KL, Ancoli-Israel S, Yaffe K. Int J Epidemiol. 2018;47:1679-86.
Mendel and urate: Acid test or random noise?
Brown EG, Goldman SM, Tanner CM. Parkinsonism Relat Disord. 2018 Aug;53:1-3.
Concordance for Parkinson’s disease in twins: a 20-year update.
Goldman SM, Marek K, Ottman R, Meng C, Comyns K, Chan P, Ma J, Marras C, Langston JW, Ross GW, Tanner CM. Ann Neurol. 2019; 85:600–5.
Environment, lifestyle and Parkinson’s disease: Implications for prevention in the next decade.
Marras C, Canning CG, Goldman SM. Mov Disord. 2019; 34:801-11.
Rotenone and Parkinson’s disease: reduced sensitivity in females.
Goldman SM, Tanner CM. Toxicol Sci. 2019;170(2):562-563.
Increased markers of cardiac vagal activity in leucine-rich repeat kinase 2-associated Parkinson's disease.
Carricarte Naranjo C, Marras C, Visanji NP, Cornforth DJ, Sanchez-Rodriguez L, Schüle B, Goldman SM, Estévez M, Stein PK, Lang AE, Jelinek HF, Machado A.
Clin Auton Res. 2019 Dec;29(6):603-614.
The NAS-NRC Twin Registry and Duke Twins Study of Memory in Aging: an update.
Gatz M, Plassman BL, Tanner CM, Goldman SM, Swan GE, Chanti-Ketterl M, Walters EE, Butler DA. Twin Res Hum Genet. 2019 Dec;22(6):757-760.
Nonsteroidal anti-inflammatory use and LRRK2 Parkinson's Disease penetrance.
San Luciano M, Tanner CM, Meng C, Marras C, Goldman SM, Lang AE, Tolosa E, Schüle B, Langston JW, Brice A, Corvol JC, Goldwurm S, Klein C, Brockman S, Berg D, Brockmann K, Ferreira JJ, Tazir M, Mellick GD, Sue CM, Hasegawa K, Tan EK, Bressman S, Saunders-Pullman R; Michael J. Fox Foundation LRRK2 Cohort Consortium.
Mov Disord. 2020 Oct;35(10):1755-1764.
Traumatic brain injury and α-synuclein: Proceed with caution.
Brown EG, Goldman SM. Neurology. 2020 Feb 25;94(8):335-336.
Parkinson’s Disease Prevention, Diagnosis and Treatment
Modulation of the microbiome in Parkinson's Disease: diet, drug, stool transplant, and beyond.
Brown EG, Goldman SM. Neurotherapeutics. 2020 Oct;17(4):1406-1417.
Gradient boosting for Parkinson's disease diagnosis from voice recordings.
Karabayir I, Goldman SM, Pappu S, Akbilgic O. BMC Med Inform Decis Mak. 2020 Sep 15;20(1):228.
Electrocardiographic changes predate Parkinson's disease onset.
Akbilgic O, Kamaleswaran R, Mohammed A, Ross GW, Masaki K, Petrovitch H, Tanner CM, Davis RL, Goldman SM. Sci Rep. 2020 Jul 9;10(1):11319.
Short-term deceleration capacity of heart rate: a sensitive marker of cardiac autonomic dysfunction in idiopathic Parkinson's disease.
Carricarte Naranjo C, Marras C, Visanji NP, Cornforth DJ, Sanchez-Rodriguez L, Schüle B, Goldman SM, Estévez M, Stein PK, Lang AE, Jelinek HF, Machado A.
Clin Auton Res. 2021 Jul 12.
The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism.
Tanner CM, Cummings SR, Schwarzschild MA, Brown EG, Dorsey ER, Espay AJ, Galifianakis NB, Goldman SM, Litvan I, Luthra N, McFarland NR, Mitchell KT, Standaert DG, Bauer DC, Greenspan SL, Beck JC, Lyles KW. NPJ Parkinsons Dis. 2021 Mar 1;7(1):16.
Remote smartphone monitoring of Parkinson's disease and individual response to therapy.
Omberg L, Chaibub Neto E, Perumal TM, Pratap A, Tediarjo A, Adams J, Bloem BR, Bot BM, Elson M, Goldman SM, Kellen MR, Kieburtz K, Klein A, Little MA, Schneider R, Suver C, Tarolli C, Tanner CM, Trister AD, Wilbanks J, Dorsey ER, Mangravite LM. Nat Biotechnol. 2021 Aug 9.
Predicting Parkinson's Disease and its pathology via simple clinical variables.
Karabayir I, Butler L, Goldman SM, Kamaleswaran R, Gunturkun F, Davis RL, Ross GW, Petrovitch H, Masaki K, Tanner CM, Tsivgoulis G, Alexandrov AV, Chinthala LK, Akbilgic O. J Parkinsons Dis. 2022;12(1):341-351.
Preventing Parkinson's Disease: An environmental agenda.
De Miranda BR, Goldman SM, Miller GW, Greenamyre JT, Dorsey ER. J Parkinsons Dis. 2022;12(1):45-68.
Childhood and Reproductive Environmental Health
Toxic environmental chemicals: The role of reproductive health professionals in preventing harmful exposures
Sutton P, Woodruff TJ, Perron J, Stotland N, Conroy JA, Miller MD, Giudice LC. Am J Obstet Gynecol. 2012;207(3):164-73.
Genetic modification of the effect of maternal household air pollution exposure on birth weight in Guatemalan newborns.
Thompson LM, Yousefi P, Peñaloza R, Balmes J, Holland N. Reprod Toxicol. 2014;50:19-26.
Children’s cancer and environmental exposures: Professional attitudes and practices.
Zachek CM, Miller MD, Hsu C, Schiffman JD, Sallen S, Metayer C, Dahl GV. J Pediatr Hematol Oncol. 2015;37(7):491-7.
Arsenic and rice: translating research to address health care providers’ needs.
Lai PY, Cottingham KL, Steinmaus C, Karagas MR, Miller MD. J Pediatr. 2015 Oct;167(4):797-803.
Early-life exposure to organophosphate pesticides and pediatric respiratory symptoms in the CHAMACOS cohort.
Raanan R, Harley KG, Balmes JR, Bradman A, Lipsett M, Eskenazi B. Environ Health Perspect. 2015;123(2):179-85.
Thyroid hormones and moderate exposure to perchlorate during pregnancy in women in Southern California.
Steinmaus C, Pearl M, Kharrazi M, Blount BC, Miller MD, Pearce EN, Valentin-Blasini L, DeLorenze G, Hoofnagle AN, Liaw J. Environ Health Perspect. 2016; 124(6):861-7.
Traffic-related air pollution and telomere length in children and adolescents living in Fresno, CA: a pilot study.
Lee EY, Lin J, Noth EM, Hammond SK, Nadeau KC, Eisen EA, Balmes JR. J Occup Environ Med. 2017 May;59(5):446-452.
Decreased lung function in 7-year-old children with early-life organophosphate exposure.
Raanan R, Balmes JR, Harley KG, Gunier RB, Magzamen S, Bradman A, Eskenazi B. Thorax. 2016;71(2):148-53.
Early-life ozone exposure associated with asthma without sensitization in Latino children.
Nishimura KK, Iwanaga K, Oh SS, Pino-Yanes M, Eng C, Keswani A, Roth LA, Nguyen EA, Thyne SM, Farber HJ, Serebrisky D, Meade K, LeNoir MA, Rodriguez-Cintron W, Borrell LN, Bibbins-Domingo K, Lurmann F, Sen Ś, Rodriguez-Santana JR, Brigino-Buenaventura E, Avila PC, Balmes JR, Kumar R, Burchard EG.
J Allergy Clin Immunol. 2016 Dec;138(6):1703-1706.e1.
Children's environmental health: Beyond national boundaries.
Miller MD, Marty MA, Landrigan PJ. Pediatr Clin North Am. 2016; 63(1):149-65.
Childhood leukemia and primary prevention.
Whitehead TP, Metayer C, Wiemels JL, Singer AW, Miller MD. Curr Probl Pediatr Adolesc Health Care. 2016 Oct;46(10):317-352.
Exposures to endocrine disrupting chemicals in consumer products -a guide for pediatricians.
Wong KH, Durrani TS. Curr Probl Pediatr Adolesc Health Care. 2017; 47(5):107-118.
Maternal perchlorate exposure in pregnancy and altered birth outcomes.
Rubin R, Pearl M, Kharrazi M, Blount BC, Miller MD, Pearce EN, Valentin-Blasini L, DeLorenze G, Liaw J, Hoofnagle AN, Steinmaus C. Environ Res. 2017;158:72-81.
Elemental sulfur use and associations with pediatric lung function and respiratory symptoms in an agricultural community (California, USA).
Raanan R, Gunier RB, Balmes JR, Beltran AJ, Harley KG, Bradman A, Eskenazi B. Environ Health Perspect. 2017 Aug 10;125(8):087007.
Cooking behaviors are related to household particulate matter exposure in children with asthma in the urban East Bay Area of Northern California.
Holm SM, Balmes J, Gillette D, Hartin K, Seto E, Lindeman D, Polanco D, Fong E. PLoS One. 2018;13(6):e0197199
Opportunities and challenges for dietary arsenic intervention.
Nachman KE, Punshon T, Rardin L, Signes-Pastor AJ, Murray CJ, Jackson BP, Guerinot ML, Burke TA, Chen CY, Ahsan H, Argos M, Cottingham KL, Cubadda F, Ginsberg GL, Goodale BC, Kurzius-Spencer M, Meharg AA, Miller MD, Nigra AE, Pendergrast CB, Raab A, Reimer K, Scheckel KG, Schwerdtle T, Taylor VF, Tokar EJ, Warczak TM, Karagas MR. Environ Health Perspect. 2018 126(8):84503.
Residential proximity to agricultural fumigant use and respiratory health in 7-year old children.
Gunier RB, Raanan R, Castorina R, Holland NT, Harley KG, Balmes JR, Fouquette L, Eskenazi B, Bradman A. Environ Res. 2018 Jul;164:93-99.
When the fetus is exposed to smoke, the developing lung is burned.
Balmes JR. Am J Respir Crit Care Med. 2019 Mar 15;199(6):684-685.
Ambient air pollution, asthma drug response, and telomere length in African American youth.
Lee EY, Oh SS, White MJ, Eng CS, Elhawary JR, Borrell LN, Nuckton TJ, Zeiger AM, Keys KL, Mak ACY, Hu D, Huntsman S, Contreras MG, Samedy LA, Goddard PC, Salazar SL, Brigino-Buenaventura EN, Davis A, Meade KE, LeNoir MA, Lurmann FW, Burchard EG, Eisen EA, Balmes JR. J Allergy Clin Immunol. 2019 Sep;144(3):839-845.e10.
Healthy air, healthy brains: Advancing air pollution policy to protect children's health.
Payne-Sturges DC, Marty MA, Perera F, Miller MD, Swanson M, Ellickson K, Cory-Slechta DA, Ritz B, Balmes J, Anderko L, Talbott EO, Gould R, Hertz-Picciotto I.
Am J Public Health. 2019 109:550-4
Do we know how best to disinfect child care sites in the United States? A review of available disinfectant efficacy data and health risks of the major disinfectant classes.
Holm SM, Leonard V, Durrani T, Miller MD. Am J Infect Control. 2019;47:82-91
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children.
Neophytou AM, Oh SS, Hu D, Huntsman S, Eng C, Rodríguez-Santana JR, Kumar R, Balmes JR, Eisen EA, Burchard EG.
Environ Epidemiol. 2019 Jun 19;3(3):e048.
Lung health and exposure to air pollution in Malawian children (CAPS): a cross-sectional study.
Rylance S, Nightingale R, Naunje A, Mbalume F, Jewell C, Balmes JR, Grigg J, Mortimer K. Thorax. 2019 Nov;74(11):1070-1077.
Where there's smoke, kids will cough and wheeze.
Balmes JR. Ann Am Thorac Soc. 2020 Mar;17(3):276-277.
Certified food dyes in over the counter medicines and supplements marketed for children and pregnant women.
Lehmkuhler AL, Miller MD, Bradman A, Castroina R, Mitchell AE. Food Chem Toxicol. 2020 Sep;143:111499.
ATS core curriculum 2020. Pediatric pulmonary medicine.
Gross JE, McCown MY, Okorie C, Bishay LC, Dy FJ, Rettig JS, Baker CD, Balmes JR, Barber AT, Bose SK, Casey A, Hawkins SMM, Kass A, Keim G, Mokhallati N, Montgomery G, Peranteau WH, Serrano R, Vece TJ, Yehya N, Boyer D, Hayes MM. ATS Sch. 2020 Dec 30;1(4):456-475.
Traffic-related air pollution, biomarkers of metabolic dysfunction, oxidative stress, and CC16 in children.
Zhang AL, Balmes JR, Lutzker L, Mann JK, Margolis HG, Tyner T, Holland N, Noth EM, Lurmann F, Hammond SK, Holm SM. J Expo Sci Environ Epidemiol. 2021 Aug 20.
Traffic-related air pollution is associated with glucose dysregulation, blood pressure, and oxidative stress in children.
Mann JK, Lutzker L, Holm SM, Margolis HG, Neophytou AM, Eisen EA, Costello S, Tyner T, Holland N, Tindula G, Prunicki M, Nadeau K, Noth EM, Lurmann F, Hammond SK, Balmes JR.Environ Res. 2021 Apr;195:110870.
Air pollution exposure is linked with methylation of immunoregulatory genes, altered immune cell profiles, and increased blood pressure in children.
Prunicki M, Cauwenberghs N, Lee J, Zhou X, Movassagh H, Noth E, Lurmann F, Hammond SK, Balmes JR, Desai M, Wu JC, Nadeau KC. Sci Rep. 2021 Feb 18;11(1):4067.
The relationship between air pollutants and maternal socioeconomic factors on preterm birth in California urban counties.
Mekonnen ZK, Oehlert JW, Eskenazi B, Shaw GM, Balmes JR, Padula AM. J Expo Sci Environ Epidemiol. 2021 May;31(3):503-513.
Potential impacts of synthetic food dyes on activity and attention in children: a review of the human and animal evidence.
Miller MD, Steinmaus C, Golub MS, Castorina R, Thilakartne R, Bradman A, Marty MA. Environ Health. 2022 Apr 29;21(1):45.
Dietary exposure to United States Food and Drug Administration-approved synthetic food colors in children, pregnant women, and women of childbearing age living in the United States.
Bradman A, Castorina R, Thilakaratne R, Gillan M, Pattabhiraman T, Nirula A, Marty M, Miller MD. Int J Environ Res Public Health. 2022 Aug 5;19(15):9661.
The association between ambient PM2.5 and low birth weight in California.
Lee J, Costello S, Balmes JR, Holm SM. Int J Environ Res Public Health. 2022 Oct 19;19(20):13554.
Dataset of FD&C certified food dyes in foods commonly consumed by children.
Lehmkuhler AL, Miller MD, Bradman A, Castorina R, Chen MA, Xie T, Mitchell AE. Data Brief. 2022 Dec 7;46:108806.
Can breathing poor-quality air lead to poor-quality sleep in children?
Balmes JR. Am J Respir Crit Care Med. 2023 Mar 1;207(5):510-511.
Associations between prenatal and early-life air pollution exposure and lung function in young children: Exploring influential windows of exposure on lung development.
Neophytou AM, Lutzker L, Good KM, Mann JK, Noth EM, Holm SM, Costello S, Tyner T, Nadeau KC, Eisen EA, Lurmann F, Hammond SK, Balmes JR. Environ Res. 2023 Apr 1;222:115415.
Climate Medicine
Climate change. A global threat to cardiopulmonary health.
Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Am J Respir Crit Care Med. 2014;189:512-9
Survey of international members of the American Thoracic Society on climate change and health.
Sarfaty M, Kreslake J, Ewart G, Guidotti TL, Thurston GD, Balmes JR, Maibach EW. Ann Am Thorac Soc. 2016 Oct;13(10):1808-1813.
The last Summer Olympics? Climate change, health, and work outdoors.
Smith KR, Woodward A, Lemke B, Otto M, Chang CJ, Mance AA, Balmes J, Kjellstrom T. Lancet. 2016;388(10045):642-4.
Environment, global climate change, and cardiopulmonary health.
Bayram H, Bauer AK, Abdalati W, Carlsten C, Pinkerton KE, Thurston GD, Balmes JR, Takaro TK. Am J Respir Crit Care Med. 2017 Mar 15;195(6):718-724.
Climate change and implications for prevention. California's efforts to provide leadership.
Balmes JR. Ann Am Thorac Soc. 2018 Apr;15(Suppl 2):S114-S117.
Global health impacts for economic models of climate change: A systematic review and meta-analysis.
Cromar KR, Anenberg SC, Balmes JR, Fawcett AA, Ghazipura M, Gohlke JM, Hashizume M, Howard P, Lavigne E, Levy K, Madrigano J, Martinich JA, Mordecai EA, Rice MB, Saha S, Scovronick NC, Sekercioglu F, Svendsen ER, Zaitchik BF, Ewart G.. Ann Am Thorac Soc. 2022 Jul;19(7):1203-1212.
COVID-19
The effect of the COVID-19 pandemic on people with Parkinson's Disease.
Brown EG, Chahine LM, Goldman SM, Korell M, Mann E, Kinel DR, Arnedo V, Marek KL, Tanner CM. J Parkinsons Dis. 2020;10(4):1365-1377.
Cycle threshold to test positivity in COVID-19 for return to work clearance in health care workers.
Domeracki S, Clapp RN, Taylor K, Lu CM, Lampiris H, Blanc PD. J Occup Environ Med. 2020 Nov;62(11):889-891.
Incidence and characteristics of delayed injection site reaction to the mRNA-1273 SARS-CoV2 vaccine (Moderna) in a cohort of hospital employees.
Jacobson MA, Zakaria A, Maung Z, Hart C, McCalmont T, Fassett M, Amerson E. Clin Infect Dis. 2021 Jun 4:ciab518.
Temporal trends in COVID-19 incidence in two healthcare worker cohorts.
McNicholas JE, Kosnik R, Blanc PD, Taylor BR, Guntur S. J Occup Environ Med. 2021 Jun 1;63(6):528-531.
Association between household exposure and cycle threshold in COVID-19 infected health care workers.
Chien A, Domeracki S, Guntur S, Taylor K, Lu CM, Lampiris H, Blanc PD. J Occup Med Toxicol. 2021 Aug 4;16(1):29.
Transmission of COVID-19 to health care personnel during exposures to a hospitalized patient - Solano County, California, February 2020.
Heinzerling A, Stuckey MJ, Scheuer T, Xu K, Perkins KM, Resseger H, Magill S, Verani JR, Jain S, Acosta M, Epson E.
MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):472-476.
Coronavirus disease among workers in food processing, food manufacturing, and agriculture workplaces.
Waltenburg MA, Rose CE, Victoroff T, Butterfield M, Dillaha JA, Heinzerling A, Chuey M, Fierro M, Jervis RH, Fedak KM, Leapley A, Gabel JA, Feldpausch A, Dunne EM, Austin C, Pedati CS, Ahmed FS, Tubach S, Rhea C, Tonzel J, Krueger A, Crum DA, Vostok J, Moore MJ, Kempher H, Scheftel J, Turabelidze G, Stover D, Donahue M, Thomas D, Edge K, Gutierrez B, Berl E, McLafferty M, Kline KE, Martz N, Rajotte JC, Julian E, Diedhiou A, Radcliffe R, Clayton JL, Ortbahn D, Cummins J, Barbeau B, Carpenter S, Pringle JC, Murphy J, Darby B, Graff NR, Dostal TKH, Pray IW, Tillman C, Rose DA, Honein MA; CDC COVID-; Emergency Response Team.
Emerg Infect Dis. 2021 Jan;27(1):243-9.
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R 3rd, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J; NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS); NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. (Arjomandi M, Collaborator). Genome Med. 2021 Apr 21;13(1):66.
Seroprevalence of SARS-CoV-2 Among Firefighters/Paramedics in San Francisco, CA.
Grant M, Harrison R, Nuñez A, Kurtz T, Phelps S, Brokaw J, Shusterman D. J Occup Environ Med. 2021 Nov 1;63(11):e807-e812.
Protecting Olympic participants from Covid-19 - The urgent need for a risk-management approach.
Sparrow AK, Brosseau LM, Harrison RJ, Osterholm MT.. N Engl J Med. 2021 Jul 1;385(1):e2.
Excess mortality associated with the COVID-19 pandemic among Californians 18-65 years of age, by occupational sector and occupation: March through November 2020.
Chen YH, Glymour M, Riley A, Balmes J, Duchowny K, Harrison R, Matthay E, Bibbins-Domingo K. PLoS One. 2021 Jun 4;16(6):e0252454.
Stress Is in the air: ambient reactive oxygen species and COVID-19.
Balmes JR. Am J Respir Crit Care Med. 2021 Jul 15;204(2):118-120.
Coccidioidomycosis and COVID-19 co-infection, United States, 2020.
Heaney AK, Head JR, Broen K, Click K, Taylor J, Balmes JR, Zelner J, Remais JV. Emerg Infect Dis. 2021;27(5):1266-1273.
Disparities in COVID-19 fatalities among working Californians.
Cummings KJ, Beckman J, Frederick M, Harrison R, Nguyen A, Snyder R, Chan E, Gibb K, Rodriguez A, Wong J, Murray EL, Jain S, Vergara X. PLoS One. 2022 Mar 29;17(3):e0266058.
Increased bloodborne pathogen exposure hotline utilization during the COVID-19 pandemic: An unexpected phenomenon.
Kiok M, Guntur S, Blanc PD, Lozato O, Domingo G, Kosnik R, Ugbaja CE, Chan N, Ramos A, Domeracki S. Workplace Health Saf. 2022 Jun;70(6):278-284.
COVID-19 in the workplace: The view from California.
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